27046-10-2

Upstream product

• 1624-53-9 2-(benzylideneamino)phenol 
• 143-15-7 1-dodecylbromide 
• 88-75-5 2-hydroxynitrobenzene 
• 824-39-5 sodium o-nitrophenate 
• 86255-27-8 silver(I) 2-nitrophenoxide 
• 10157-76-3 dodecyl 4-methylbenzenesulphonate 
• 4292-19-7 1-Iodododecane 
• 112-52-7 1-chlorododecane 
• 1124-31-8 potassium 4-nitrophenolate 
• 83027-71-8 dodecyl 2-nitrophenyl ether 

Downstream Products

• 1256341-21-5 C₂₆H₃₅NO₄ 
• 860531-91-5 2-dodecyloxy-N,N-dimethyl-aniline 

Relevant academic research and scientific papers

Synthesis and biological evaluation of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as PTP1B inhibitors

Based on the fact that petroselinic acid showed good inhibitory activity (IC50=6.99μmol/L) against protein tyrosine phophatase 1B(PTP1B) in vitro, a series of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives were designed and synthesized. The results indicated that most of the derivatives showed more potent activities against PTP1B. Especially, compound 13 had obvious activity with an IC50 of 106nmol/L in vitro.

Selective alkylation of aminophenols

O-or N-Alkylated derivatives of aminophenols are important synthetic intermediates in organic synthesis. A series of aminophenols were selectively alkylated on their hydroxyl group in good yields via benzaldehyde protection of the amino group, subsequent alkylation, and hydrolysis; or on their amino group via imination and following reduction. ARKAT USA, Inc.