27051-20-3

Basic information

• Product Name: (E)-4-(2-(quinolin-2-yl)ethenyl)benzonitrile
• Synonyms: (E)-4-(2-(quinolin-2-yl)ethenyl)benzonitrile
• CAS NO: 27051-20-3
• Molecular Weight: 256.307
• Mol File: 27051-20-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (E)-4-(2-(quinolin-2-yl)ethenyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(2-(quinolin-2-yl)ethenyl)benzonitrile(27051-20-3)
• EPA Substance Registry System: (E)-4-(2-(quinolin-2-yl)ethenyl)benzonitrile(27051-20-3)

Safety Data

• Hazardous Substances Data: 27051-20-3(Hazardous Substances Data)

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 1780-19-4 1,2,3,4-tetrahydro-2-methylquinoline 
• 91-63-4 2-methylquinoline 
• 37812-49-0 4-phenylaminomethyl-benzonitrile 

Relevant articles and documents

Direct Alkenylation of 2-Methylquinolines with Aldehydes through Synergistic Catalysis of 1,3-Dimethylbarbituric Acid and HOAc

An efficient and practical direct alkenylation of 2-methylquinolines with aldehydes has been achieved through a novel synergistic organocatalysis. The HOAc- activated 2-methylquiolines undergo a Michael addition to 1,3-dimethylbarbituric acid-activated aldehydes, followed by a retro-Michael addition to release 1,3-dimethylbarbituric acid and the target products. The transformation produced various 2-alkenylquinolines with good to excellent yields and featured mild reaction conditions, atom- and step-economy, good functional group tolerance, and operational simplicity. (Figure presented.).

Cobalt-catalyzed direct alkenylation of 2-methylquinolines with aldehydes via C(sp3)-H functionalization in water

The direct C(sp3)-H alkenylation of 2-methylquinolines with aldehydes as a simple methodology to afford 2-alkenylated quinolines is reported. In the presence of catalytic CoCl2 in water, the economically and ecologically sound transformation is proposed to proceed via the direct benzylic addition to the aldehyde followed by an elimination step to provide 2-alkenylated quinolines in good to excellent yield of up to 95%. Georg Thieme Verlag Stuttgart New York.

Protonation dependent electron transfer in 2-styrylquinolines

The absorption and emission spectra for 4′-substituted-2-trans-styrylquinoline (X = NMe2, 1; H, 2; CN, 3; NO2, 4) and 4′-N,N-dimethylamino-2-trans-styrylnaphthalene 5 were studied in various solvents and at various acid concentration