27063-27-0 Usage
Uses
Used in Pharmaceutical Industry:
4-METHYL-2-QUINOLINAMINE is used as a key intermediate in the synthesis of various pharmaceuticals for the treatment of different diseases. Its unique quinoline ring structure contributes to the development of new drugs with improved therapeutic properties.
Used in Organic Compounds Synthesis:
4-METHYL-2-QUINOLINAMINE is used as a building block in the synthesis of various organic compounds, enabling the creation of new chemical entities with diverse applications.
Used in Medicinal and Agricultural Chemicals Production:
4-METHYL-2-QUINOLINAMINE is used as an important intermediate in the production of medicinal and agricultural chemicals, contributing to the development of effective treatments and products in these fields.
Used in Research and Development:
4-METHYL-2-QUINOLINAMINE is utilized in research and development within the pharmaceutical industry, where it aids in the discovery and optimization of new drug candidates and organic compounds with potential therapeutic and practical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 27063-27-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,0,6 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 27063-27:
(7*2)+(6*7)+(5*0)+(4*6)+(3*3)+(2*2)+(1*7)=100
100 % 10 = 0
So 27063-27-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2/c1-7-6-10(11)12-9-5-3-2-4-8(7)9/h2-6H,1H3,(H2,11,12)
27063-27-0Relevant academic research and scientific papers
Cu-catalyzed aerobic oxidative cyclizations of 3-N-hydroxyamino-1,2-propadienes with alcohols, thiols, and amines to form α-O-, S-, and N-substituted 4-methylquinoline derivatives
Sharma, Pankaj,Liu, Rai-Shung
supporting information, p. 4590 - 4594 (2015/03/18)
A one-pot, two-step synthesis of α-O-, S-, and Nsubstituted 4-methylquinoline derivatives through Cu-catalyzed aerobic oxidations of N-hydroxyaminoallenes with alcohols, thiols, and amines is described. This reaction sequence involves an initial oxidation of N-hydroxyaminoallenes with NuH (Nu = OH, OR, NHR, and SR) to form 3-substituted 2-en-1-ones, followed by Bronsted acid catalyzed intramolecular cyclizations of the resulting products. Our mechanistic analysis suggests that the reactions proceed through a radical-type mechanism rather than a typical ni-trone-intermediate route. The utility of this new Cu-catalyzed reaction is shown by its applicability to the synthesis of several 2-amino-4-methylquinoline derivatives, which are known to be key precursors to several bioactive molecules.
