27065-94-7

Basic information

• Product Name: (3-FORMYL-INDOL-1-YL)-ACETIC ACID ETHYL ESTER
• Synonyms: ETHYL (3-FORMYL-INDOL-1-YL)-ACETATE;(3-FORMYL-INDOL-1-YL)-ACETIC ACID ETHYL ESTER;3-FORMYL-1H-INDOLE-1-ACETIC ACID ETHYL ESTER;ethyl (3-formyl-1H-indol-1-yl)acetate;ethyl 2-(3-forMyl-1H-indol-1-yl)acetate;2-(3-formyl-1-indolyl)acetic acid ethyl ester;2-(3-formylindol-1-yl)acetic acid ethyl ester;ethyl 2-(3-formylindol-1-yl)acetate
• CAS NO: 27065-94-7
• Molecular Formula: C13H13NO3
• Molecular Weight: 231.25
• Mol File: 27065-94-7.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 397.5 °C at 760 mmHg
• Flash Point: 194.2 °C
• Appearance: /
• Density: 1.18 g/cm³
• Vapor Pressure: 1.58E-06mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (3-FORMYL-INDOL-1-YL)-ACETIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-FORMYL-INDOL-1-YL)-ACETIC ACID ETHYL ESTER(27065-94-7)
• EPA Substance Registry System: (3-FORMYL-INDOL-1-YL)-ACETIC ACID ETHYL ESTER(27065-94-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 27065-94-7(Hazardous Substances Data)

Usage

General Description

(3-Formyl-indol-1-yl)-acetic acid ethyl ester is a chemical compound that belongs to the class of indole derivatives. It is an ester of acetic acid and contains a formyl group attached to the indole ring. The compound has potential applications in pharmaceutical and medicinal chemistry due to its unique structure and potential biological activities. This chemical has shown promising antioxidant, antimicrobial, and anti-inflammatory properties, which make it a potential candidate for drug development. Its structure and properties make it a significant compound in the field of organic chemistry and drug discovery.

InChI:InChI=1/C13H13NO3/c1-2-17-13(16)8-14-7-10(9-15)11-5-3-4-6-12(11)14/h3-7,9H,2,8H2,1H3

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 105-36-2 ethyl bromoacetate 
• 105-39-5 chloroacetic acid ethyl ester 
• 75629-45-7 (Z)-3-(pyrrolidin-1-ylmethylene)-3H-indole 
• 120-72-9 indole 
• 75629-56-0 1-ethoxycarbonylmethyl-3-(1-pyrrolidinylmethylene)-3H-indolium bromide 

Downstream Products

• 1616477-50-9 C₁₉H₁₉NO₃ 
• 138423-98-0 3-formyl-indole-1-yl-acetic acid 

Relevant articles and documents

Phenanthro [9,10-d] imidazole derivatives containing indoles as well as synthesis and application of phenanthro [9,10-d] imidazole derivatives containing indoles

The invention discloses phenanthro [9,10-d] imidazole derivatives containing indoles as well as a preparation method and application of the phenanthro [9,10-d] imidazole derivatives containing the indoles and belongs to the field of biological organic synthesis. The phenanthro [9,10-d] imidazole derivatives containing the indoles, disclosed by the invention, are characterized in that an indole pharmacophore with anticancer activity is introduced on phenanthro imidazole to increase conjugate area and improve biological activities of molecules, thereby improving an antitumor effect. The preparation method of the phenanthro [9,10-d] imidazole derivatives containing the indoles, disclosed by the invention, is characterized in that by taking indole-3-formaldehyde as a starting point, different chains (halides) are modified at N-positions, and are finally condensed with 9,10-phenanthrenequinone to synthesize the phenanthro [9,10-d] imidazole derivatives containing the indoles which have a restraining force for the growth of tumor cells in vitro.

Solid-liquid phase alkylation of n-heterocycles: Microwave-assisted synthesis as an environmentally friendly alternative

The solid-liquid phase alkylation of a variety of five-membered N-heterocycles (carbazole, imidazole, benzimidazole, and indole-3-carbaldehyde) was carried out under different conditions. The use of alkali carbonate in dimethylformamide or in MeCN (in the latter case, in the presence of a phase-transfer catalyst) is a suitable method to prepare the corresponding N-alkylated products in an efficient way. In most cases, the solventless, microwave-assisted reaction is an environmentally friendly alternative to traditional methods. Copyrigh

3,4,(5)-SUBSTITUTED TETRAHVDROPYRIDINES

Organic Compounds 3,4(,5)-substituted tetrahydropyridine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4(,5)- substituted tetrahydropyridine compound, and/or a method of treatment comprising administering a 3,4(,5)-substituted tetrahydropyridine compound, a method for the manufacture of a 3,4(,5)- substituted tetrahydropyridine compound, and novel intermediates and partial steps for its synthesis. The 3,4(,5)- substituted tetrahydropyridine compounds have the formula I wherein the substituents and symbols are as described in the specification.