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2711-99-1

1-(4-fluorophenyl)-1-phenylhydrazine is an organic compound with the chemical formula C12H10FN2. It is a derivative of phenylhydrazine, featuring a fluorine atom attached to the 4-position of the phenyl ring. This molecule is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as an intermediate in the production of certain antipsychotic drugs. The presence of the fluorine atom can significantly influence the compound's reactivity and physical properties, such as its lipophilicity, which can be crucial for its biological activity. The compound is typically synthesized through a reaction involving 4-fluorophenylmagnesium bromide and phenylhydrazine, and it is important to handle it with care due to its potential reactivity and the need to control for safety in chemical processes.

2711-99-1

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2711-99-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2711-99-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,1 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2711-99:
(6*2)+(5*7)+(4*1)+(3*1)+(2*9)+(1*9)=81
81 % 10 = 1
So 2711-99-1 is a valid CAS Registry Number.

2711-99-1Relevant articles and documents

Palladium-catalyzed monoarylation of arylhydrazines with aryl tosylates

Huang, Yange,Choy, Pui Ying,Wang, Junya,Tse, Man-Kin,Raymond Wai-Yin Sun,Albert Sun-Chi Chan,Kwong, Fuk Yee

, p. 14664 - 14673 (2020/12/29)

A palladium-catalyzed C-N bond coupling reaction between arylhydrazines and aryl tosylates for facile synthesis of unsymmetrical N,N-diarylhydrazines has been developed. Employing the catalyst system of Pd(TFA)2 associated with newly developed phosphine ligand L1, the monoarylation of arylhydrazine proceeds smoothly to afford desired products in good-to-excellent yields (up to 95%) with good functional group compatibility. This method provides an alternative synthetic pathway for accessing structurally diversified N,N-diarylhydrazines from simple and easily accessible coupling components.

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