27181-83-5

Upstream product

• 14191-95-8 4-cyanomethylphenol 
• 487-71-8 Iretol 
• 13708-94-6 7-benzyloxy-5-hydroxy-3-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one 
• 27181-82-4 4-Hydroxybenzyl-4-benzyloxy-2,6-dihydroxy-3-methoxyphenylketon 

Downstream Products

• 27181-85-7 5,7-dihydroxy-3-(4-hydroxy-phenyl)-8-methoxy-4-oxo-4H-chromene-2-carboxylic acid ethyl ester 
• 13111-57-4 4',5,7-trihydroxy-8-methoxyisoflavone 
• 548-77-6 tectorigenin 
• 101446-12-2 5,7-dihydroxy-3-(4-hydroxy-phenyl)-8-methoxy-4-oxo-4H-chromene-2-carboxylic acid 
• 27181-88-0 5,7-diacetoxy-3-(4-acetoxy-phenyl)-8-methoxy-chromen-4-one 
• 1155265-07-8 2-(4-hydroxyphenyl)-1-(2,4,6-trihydroxy-3-methoxyphenyl)ethanone oxime 

Relevant academic research and scientific papers

Efficient method for the synthesis of tectorigenin

Tectorigenin, isolated from the rhizomes of Belamcanda chinensis, shows a wide variety of biological activities. The interest in its biological activities has been matched by a corresponding interest in its synthesis. We herein reported a convenient synth

Polyphenols based on isoflavones as inhibitors of Helicobacter pylori urease

Twenty polyphenols were synthesized and evaluated for their effect on Helicobacter pylori urease. Among these compounds, 4-(p-hydroxyphenethyl)pyrogallol (15) (IC50 = 0.03 mM) and 7,8,4′-trihydroxyisoflavone (19) (IC50 = 0.14 mM) showed potent inhibitory activities, and inhibited Helicobacter pylori urease in a time-dependent manner. The structure-activity relationship of these polyphenols revealed: the two ortho hydroxyl groups were essential for inhibitory activity of polyphenol. When the C-ring of isoflavone was broken, the inhibitory activity markedly decreased. As for deoxybenzoin, the carboxyl group was clearly detrimental.