272772-52-8

Upstream product

• 272772-39-1 ethyl (S)-(-)-6-(N-tert-butoxycarbonyl-N-4-methoxybenzyl)amino-3-ethoxy-7-phenylhepta-2,4-dienoate 
• 272772-40-4 (4S,5S)-(-)-4-benzyl-5-(3-ethoxycarbonyl-2-oxo)propyl-3-N-(4-methoxybenzyl)-2-oxazolidinone 
• 199926-80-2 ethyl (S)-(-)-6-(N-tert-butoxycarbonyl)amino-3-ethoxy-7-phenylhepta-2,4-dienoate 
• 72155-45-4 Boc-L-phenylalaninal 
• 77-76-9 2,2-dimethoxy-propane 
• 272772-50-6 (4S,5S)-(-)-4-benzyl-5-(2,4-dihydroxybutyl)-3-(N-4-methoxybenzyl)-2-oxazolidinone 

Relevant academic research and scientific papers

Synthesis and reaction of chiral 4,5-disubstituted 2-oxazolidinones from 3-ethoxy-6-(N-alkyl-N-tert-butoxy- carbonyl)aminohexa-2,4-dienoates in the presence of concentrated sulfuric acid supported on silica gel

Reaction of chiral 3-ethoxy-6-(N-alkyl-N-tert-butoxycarbonyl)amino-hexa- 2,4-dienoates (3) and related compounds with 97% concentrated sulfuric acid supported on silica gel proceeded stereo- and regio-selectively to yield chiral 4,5-disubstituted N-alkyl-2-oxazolidinones (7). Under the limited conditions, 7 were converted into N-alkyl-2-pyrrolylacetates (8) and 2- oxazolidinone derivatives (12) which may serve as a chiral auxiliary.