27292-50-8

Basic information

• Product Name: 3-PIPERIDINOPHENOL
• Synonyms: 3-PIPERIDINOPHENOL;Nsc23894;3-(Piperidin-1-yl)phenol
• CAS NO: 27292-50-8
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.24
• Mol File: 27292-50-8.mol
• Article Data: 16

Chemical Properties

• Melting Point: 123-124 °C
• Boiling Point: 338.9 °C at 760 mmHg
• Flash Point: 183.6 °C
• Appearance: /
• Density: 1.106 g/cm³
• Vapor Pressure: 4.84E-05mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.37±0.10(Predicted)
• CAS DataBase Reference: 3-PIPERIDINOPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PIPERIDINOPHENOL(27292-50-8)
• EPA Substance Registry System: 3-PIPERIDINOPHENOL(27292-50-8)

Safety Data

• Hazardous Substances Data: 27292-50-8(Hazardous Substances Data)

Usage

General Description

3-Piperidinophenol is a chemical compound with the molecular formula C11H15NO. It is a white to off-white crystalline powder with a molecular weight of 177.24 g/mol. 3-Piperidinophenol is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It has potentially useful properties as an anti-inflammatory and anesthetic agent, and has been studied for its potential use in the treatment of pain and neuroinflammation. Additionally, 3-Piperidinophenol has been investigated for its potential use as a stabilizer in the formulation of pharmaceutical products, due to its ability to prevent the degradation of active ingredients in formulations. Overall, 3-Piperidinophenol is a versatile and potentially valuable chemical compound with a range of potential applications in the pharmaceutical and medical industries.

InChI:InChI=1/C11H15NO/c13-11-6-4-5-10(9-11)12-7-2-1-3-8-12/h4-6,9,13H,1-3,7-8H2

Upstream product

• 32040-06-5 N-(3-methoxyphenyl)piperidine 
• 110-89-4 piperidine 
• 108-43-0 3-monochlorophenol 
• 591-20-8 3-Bromophenol 
• 111-24-0 1,5-dibromo-pentane 
• 591-27-5 m-Hydroxyaniline 
• 536-90-3 m-Anisidine 
• 111-29-5 1 ,5-pentanediol 
• 16179-65-0 3-(piperidin-1-yl)cyclohex-2-en-1-one 
• 108-94-1 cyclohexanone 
• 27969-75-1 3‐(piperidin‐1‐yl)aniline 
• 628-76-2 1,5-dichloropentane 

Downstream Products

• 96649-16-0 3-(1-piperidinyl)phenyl diethylcarbamate 
• 1229439-27-3 5,5'-bis-piperidino-2,2'-methandiyl-di-phenol 
• 27292-59-7 2-nitroso-5-(piperidin-1-yl)phenol 
• 1032716-21-4 1-(3-methoxy-4-nitrosophenyl)piperidine 
• 32040-06-5 N-(3-methoxyphenyl)piperidine 
• 96649-21-7 2-hydroxy-4-(piperidin-1-yl)benzaldehyde 
• 1152500-28-1 C₁₅H₂₁NO 

Relevant articles and documents

Formation of 3-Aminophenols from Cyclohexane-1,3-diones

meta-Aminophenols are formed by the action of DBU on 3-amino-2-chlorocyclohex-2-en-1-ones at room temperature in MeCN. The chloro compounds are generated by treating 3-aminocyclohex-2-en-1-ones with the easily prepared halogenating agent BnNMe3·ICl2 in Me

NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION

Nerve-specific fluorophore formulations for direct or systemic administration are described. The formulations can be used in fluorescence-guided surgery (FGS) to aid in nerve preservation during surgical interventions.

Inter-alkane amidogen phenolic synthetic method (by machine translation)

Inter-alkane amidogen phenolic synthetic method, its characteristic is: 1st step, between the two alkane amidogen acyl aniline and sulfuric acid aqueous solution mixing and heating to 50 - 110 °C, thermal insulation reaction of aniline [...] sulfuric acid aqueous solution; 2nd step, continue to drip the sodium nitrite aqueous solution, sodium nitrite aqueous solution for dropping temperature of - 10 - 20 °C, drop bi yu 5 - 30 °C insulation, [...] aniline obtained diazonium salt of the sulfuric acid aqueous solution; 3rd step, [...] aniline diazonium salt of the sulfuric acid aqueous solution is directly heated to 45 - 110 °C, thermal insulation, in the hydrolysis reaction of the diazonium salt, cooling after treatment, to obtain the product between two alkane amidogen phenol; three-step required by the reaction of sulfuric acid in the 1st step reaction in the finished disposable adding; a three-step reaction in a finish step by step in the pot. The method of the invention with raw materials are cheap, abundant, synthetic high security of the process, the product yield is high, the three waste less pollution and the like, has high industrial value. (by machine translation)