27305-49-3

Usage

Uses

Used in Pharmaceutical Industry:
1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate is used as a pharmaceutical compound for its potential therapeutic effects. Its unique structure and properties make it a promising candidate for the development of new drugs to treat various diseases and disorders.
Used in Medicinal Chemistry Research:
1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate is used as a research molecule in medicinal chemistry. Its specific structure and functional groups allow scientists to study its interactions with biological targets and explore its potential applications in drug development.
Used in Biotechnology Applications:
1-oxo-1,5-naphthyridin-1-ium-5(1H)-olate is used in biotechnology for its potential applications in the development of new therapies and diagnostic tools. Its unique chemical properties make it a valuable molecule for further exploration and utilization in the biotechnology field.

Upstream product

• 462-08-8 pyridin-3-ylamine 
• 254-79-5 1,5-naphthyridine 
• 7722-84-1 dihydrogen peroxide 
• 64-19-7 acetic acid 
• 79-21-0 peracetic acid 

Downstream Products

• 27017-66-9 2,6-dichloro-1,5-naphthyridine 
• 27017-70-5 1,5-dihydro-1,5-naphthyridine-2,6-dione 

Relevant academic research and scientific papers

Linear-shaped thermally activated delayed fluorescence emitter using 1,5-naphthyridine as an electron acceptor for efficient light extraction

In this study, we developed a donor-π-acceptor-π-donor-type thermally activated delayed fluorescence (TADF) emitter (NyDPAc) using 1,5-naphthyridine as a core moiety. NyDPAc exhibited a high horizontal dipole ratio and thus a high external quantum efficiency (20.9%) even at a relatively low photoluminescence quantum yield (57%). 1,5-naphthyridine as an electron acceptor represents a promising core moiety for efficient TADF materials.

TAU PET IMAGING LIGANDS

The present invention relates to novel, selective radiolabelled tau ligands which are useful for imaging and quantifying tau aggregates, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue or a subject, in vitro or in vivo, and to precursors of said compounds.

Discovery of N-(Pyridin-4-yl)-1,5-naphthyridin-2-amines as Potential Tau Pathology PET Tracers for Alzheimer’s Disease

A mini-HTS on 4000 compounds selected using 2D fragment-based similarity and 3D pharmacophoric and shape similarity to known selective tau aggregate binders identified N-(6-methylpyridin-2-yl)quinolin-2-amine 10 as a novel potent binder to human AD aggreg

SUBSTITUTED NAPHTHYRIDINES AS ACCEPTOR MOLECULES FOR ELECTRONIC DEVICES

The present invention provides the compounds of formula (1) wherein p is 1, 2, 3, 4, 5 or 6, and10 Ar1 is at each occurrence a 5 to 9 membered heteroaromatic moiety, which may be substituted with one or more substituents independently from each other selected from the group consisting of C1-20-alkyl, O-C1-20-alkyl, C(O)-C1-20-alkyl, C(O)-O-C1-20-alkyl, phenyl, F, Cl and Br, wherein C1-20-alkyl, C1-20-alkyl, O-C1-20-alkyl, C(O)-C1-20-alkyl and C(O)-O-C1-20-alkyl may be substituted with one or more substituents independently from each other selected from the group consisting of F, Cl, Br and phenyl, wherein phenyl may be substituted with one or more substituents independently from each other selected from the group consisting of F, Cl, Br and C1-10-alkyl, and electronic devices comprising these compounds.