27315-08-8Relevant academic research and scientific papers
High yielding microwave-assisted synthesis of tri-substituted 1,3,5-triazines using Pd-catalyzed aryl and heteroarylamination
Dao, Pascal,Garbay, Christiane,Chen, Huixiong
experimental part, p. 3856 - 3860 (2012/06/30)
A rapid and efficient Pd-catalyzed aryl and heteroarylamination under microwave irradiation has been developed for various tri-substituted triazines that can serve as versatile building blocks for both supramolecular and medicinal chemistry research. Particularly valuable features of this method included the short reaction time, good yield, and convenient operation.
A facile synthesis of 6H-[1,3,5]triazino[2,1-b]quinazolin-6-ones
Abbott, Shaun,Cloutier, Josee,Houde, Karine,Penney, Christopher,Zacharie, Boulos
experimental part, p. 1733 - 1740 (2011/07/08)
Triazinoquinazolinone derivatives are synthesized by cyclization of aminobenzamide-substituted triazine compounds in the presence of a proton source such as trifluoroacetic acid or hydrochloric acid. The reaction is mild, general, and gives high yield (>90%) of the cyclized product. This procedure allows, for the first time, access to triazinoquinazolinone compounds bearing different functionalities on the benzene and triazine moieties that are not available by other routes. Georg Thieme Verlag Stuttgart - New York.
The synthesis of novel 2,4,6-trisubstituted 1,3,5-triazines: A search for potential murf enzyme inhibitors
Sosic, Izidor,Stefane, Bogdan,Kovac, Andreja,Turk, Samo,Blanot, Didier,Gobec, Stanislav
experimental part, p. 91 - 115 (2010/05/19)
A series of new 2,4,6-trisubstituted 1,3,5-triazines, possessing a variety of substituents (-OH, -SH, -OMe, -Cl, -HNR, -SR and amino acid moieties), were synthesized and evaluated for the inhibition of the bacterial peptidoglycan biosynthesis enzyme MurF.
