27331-97-1

Basic information

• Product Name: ethyl α-hydroxyimino-β-oxo-4-methoxybenzenepropionate
• Synonyms: ethyl α-hydroxyimino-β-oxo-4-methoxybenzenepropionate
• CAS NO: 27331-97-1
• Molecular Weight: 251.239
• Mol File: 27331-97-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl α-hydroxyimino-β-oxo-4-methoxybenzenepropionate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl α-hydroxyimino-β-oxo-4-methoxybenzenepropionate(27331-97-1)
• EPA Substance Registry System: ethyl α-hydroxyimino-β-oxo-4-methoxybenzenepropionate(27331-97-1)

Safety Data

• Hazardous Substances Data: 27331-97-1(Hazardous Substances Data)

Upstream product

• 94-30-4 ethyl 4-methoxybenzoate 
• 2881-83-6 ethyl 4-methoxybenzoylacetate 

Downstream Products

• 153829-67-5 methyl (2S,3S)-(+)-2-bromo-3-hydroxy-3-(4-methoxyphenyl)propionate 
• 153829-66-4 (2S,3S)-2-amino-3-hydroxy-3-(4-methoxyphenyl)propanoic acid 
• 137173-40-1 (2S,3R)-methyl p-methoxycinnamate epoxide 
• 105560-93-8 methyl (2R,3S)-3-(4-methoxyphenyl)glycidate 

Relevant articles and documents

A new enantioselective synthesis of (2R,3S)-3-(4-methoxyphenyl)glycidic ester via the enzymatic hydrolysis of erythro-N-acetyl-β-(4- methoxyphenyl)serine

Enantioselective synthesis of (2R,3S)-3-(4-methoxyphenyl)glycidic ester ((2R,3S)-1) via the enzymatic hydrolysis of erythro-N-acetyl-β-(4- methoxyphenyl)serine (9) was investigated. Treatment of the obtained α- amino acid (-)-10 with NaNO2-KBr-dilute H2SO4, esterification, and subsequent oxiran-ring closure of the halohydrin gave the target compound (2R,3S)-1 with high enantiomeric excess (94% ee).