273402-73-6

Upstream product

• 199613-48-4 5-tert-butyl-dimethylsilyloxy-(5S)-2-cyclohexenone 
• 199613-50-8 (1RS,3S)-1-hydroxy-3-(tert-butyldimethylsiloxy)bicyclo<3.1.0>hexane 
• 199613-49-5 (S)-ethyl 3-(tert-butyldimethylsiloxy)-5-hexenoate 

Downstream Products

• 274901-11-0 [5-(tert-butyl-dimethyl-silanyloxy)-1,2,3-trihydroxy-cyclohexyl]-acetic acid tert-butyl ester 
• 274901-13-2 [1-acetoxy-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexyl]-acetic acid tert-butyl ester 
• 273402-76-9 [3,5-bis-(tert-butyl-dimethyl-silanyloxy)-1,2-dihydroxy-cyclohexyl]-acetic acid tert-butyl ester 
• 274901-14-3 [3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-acetic acid tert-butyl ester 
• 273402-79-2 [3,5-bis-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-2-oxo-cyclohexyl]-acetic acid tert-butyl ester 
• 81506-23-2 <3S-(1E,3α,5β)>-<3,5-bis<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>acetic acid ethyl ester 
• 138608-61-4 (3aR,7aS)-2,2-Dimethyl-4-phenyl-3a,7a-dihydro-benzo[1,3]dioxole 

Relevant academic research and scientific papers

Chemical synthesis of optically active cis-cyclohexa-3,5-diene-1,2-diols and their 5-2H-derivatives

A variety of optically active 3-substituted cis-cyclohexane-3,5-dien-1,2-diol acetonides were readily prepared from chiral 5-(tert-butyldimethylsilyloxy)-2-cyclohexenone through a seven-step reaction in good overall yield. The synthesis also allowed prepa

Asymmetric synthesis of 1 α,25-dihydroxyvitamin D3 A-ring precursor starting with 5-tert-butyldimethylsiloxy-2-cyclohexenone

The A-ring precursor of 1 α,25-dihydroxyvitamin D3 [(E)-4] has been prepared starting from the (5S)-tert-butyldimethylsiloxy-2-cyclohexenone [(S)-1] via eight steps in 19% overall yield, where a catalytic osmium dihydroxylation which sets the stereochemistry of the hydroxyl group at C1 and a regioselective protection of the hydroxy group as a TBS-ether are the key steps. (C) 2000 Elsevier Science Ltd.