274-95-3 Usage
Description
Imidazo[1,2-a]pyrimidine is a heterocyclic compound characterized by a fused imidazole and pyrimidine ring system. It serves as a versatile building block in organic synthesis and is recognized for its core structure in a multitude of biologically active compounds, encompassing both pharmaceuticals and agrochemicals. The derivatives of imidazo[1,2-a]pyrimidine display a diverse array of biological activities, including antiviral, anticancer, antifungal, and antibacterial properties. Its significant pharmacological potential has garnered considerable interest from researchers, positioning it at the forefront of drug discovery initiatives. Moreover, imidazo[1,2-a]pyrimidine also holds promise in the realms of materials science and as ligands in coordination chemistry.
Uses
Used in Pharmaceutical Industry:
Imidazo[1,2-a]pyrimidine is used as a core structure for the development of biologically active compounds due to its wide range of biological activities, such as antiviral, anticancer, antifungal, and antibacterial properties. Its presence in various pharmaceuticals is attributed to its ability to modulate different biological pathways and target specific diseases.
Used in Agrochemical Industry:
Imidazo[1,2-a]pyrimidine is utilized as a key component in the synthesis of agrochemicals, where it contributes to the development of compounds with pesticidal properties, thereby enhancing crop protection and yield.
Used in Materials Science:
Imidazo[1,2-a]pyrimidine is employed in materials science for its potential to contribute to the creation of novel materials with unique properties, such as improved stability, reactivity, or selectivity in various applications.
Used as Ligands in Coordination Chemistry:
Imidazo[1,2-a]pyrimidine serves as effective ligands in coordination chemistry, where they play a crucial role in the formation of coordination complexes. These complexes find applications in catalysis, sensing, and other areas, capitalizing on the versatile coordination modes and electronic properties of imidazo[1,2-a]pyrimidine.
Check Digit Verification of cas no
The CAS Registry Mumber 274-95-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,7 and 4 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 274-95:
(5*2)+(4*7)+(3*4)+(2*9)+(1*5)=73
73 % 10 = 3
So 274-95-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H5N3/c1-2-7-6-8-3-5-9(6)4-1/h1-5H
274-95-3Relevant articles and documents
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Marchetti et al.
, p. 455 (1975)
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Organic compound comprising pyrimidine and organic electroluminescent device comprising the same
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Paragraph 0069; 0072; 0073; 0076; 0077, (2018/02/10)
The present invention relates to an organic aromatic organic compound containing pyridine, and an organic electroluminescent device using the same, wherein the compound may be used as thermally activated delayed fluorescent (TADF) material due to having little energy difference between an excited singlet state and an excited triplet state. Further, the compound of the present invention may be used in an organic light-emitting diode to improve efficiency of the organic light-emitting diode and lower driving voltage thereof.COPYRIGHT KIPO 2017
Synthesis and antibacterial activity of some imidazo[1,2-a[pyrimidine derivatives
Rival,Grassy,Michel
, p. 1170 - 1176 (2007/10/02)
A series of 75 imidazo[1,2-a]pyrimidine derivatives were synthesized. The 'in vitro' antibacterial activity of these compounds and their corresponding α-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity.
