27427-66-3

Usage

Uses

Used in Pharmaceutical Synthesis:
3,6-dichloropyridazine-4-carboxamide is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Organic Chemistry:
In the field of organic chemistry, 3,6-dichloropyridazine-4-carboxamide is used as a building block for the creation of complex organic molecules. Its versatile structure enables the formation of a wide range of chemical entities with diverse applications.
Used in Agricultural Applications:
3,6-dichloropyridazine-4-carboxamide may be employed in agriculture as a component in the development of new pesticides or herbicides. Its chemical properties could contribute to the creation of more effective and targeted crop protection agents.
Used in Industrial Processes:
In industrial settings, 3,6-dichloropyridazine-4-carboxamide could be utilized in the production of various chemicals and materials. Its unique structure may offer advantages in the synthesis of specific industrial compounds or in the development of new materials with desired properties.
Safety Considerations:
Due to the potential hazards associated with 3,6-dichloropyridazine-4-carboxamide, it is essential to handle this chemical with caution. Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, should be implemented to minimize risks during its use in various applications.

InChI:InChI=1/C5H3Cl2N3O/c6-3-1-2(5(8)11)4(7)10-9-3/h1H,(H2,8,11)

Upstream product

• 124-41-4 sodium methylate 
• 34127-22-5 ethyl 3,6-dichloropyridazine-4-carboxylate 
• 51149-08-7 3,6-dichloropyridazin-4-carboxylic acid 
• 6531-08-4 3,6-dichloropyridazine-5-carboxylic acid chloride 

Downstream Products

• 1145786-53-3 6-chloro-3-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-4-pyridazinecarboxamide 
• 35857-93-3 3,6-dichloropyridazine-4-carbonitrile 
• 2125-94-2 1H-pyrazolo[3,4-c]pyridazin-3-amine 

Relevant academic research and scientific papers

6,7-DIAZAINDAZOLE AND 6,7-DIAZAINDOLE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

ALKYNYL ALCOHOLS AND METHODS OF USE

The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over- activation of NF-kB signaling is observed.

PYRIDAZINE DERIVATIVES FOR INHIBITING BETA AMYLOID PEPTIDE PRODUCTION

The present invention relates to novel compounds that inhibit the production of β- amyloid peptide (1-42), processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.

TRIAZOLO-PYRIDAZINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF NEUROPATHIC PAIN

The present invention is directed to a method of use of triazolo-pyridazine compounds in the treatment of neuropathic pain. The present invention is also directed to the use of triazolo-pyridazine compounds in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, bipolar disorders, and panic, as well as in the treatment of pain, Parkinson’s disease, cognitive dysfunction, epilepsy, circadian rhythm and sleep disorders - such as shift-work induced sleep disorder and jet-lag, drug addiction, drug abuse, drug withdrawal and other diseases. The present invention is also directed to novel triazolo-pyridazine compounds that selectively bind to α2δ-1 subunit of Ca channels.

PYRIDAZINIL QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS

The invention concerns quinazoline derivatives of Formula (I) wherein Z is an O, S, SO, SO2, N(R2) or C(R2)(R3) group wherein each R2 or R3 group is hydrogen or (1-8C)alkyl, m is 1, 2 or 3, each R1 group has any of the meanings defined in the description, Ra is halogeno or (1-6C)alkoxy, Rb is halogeno or (1-6C)alkoxy, and Rc is hydrogen, halogeno, (1-8C)alkyl or (1-6C)alkoxy, or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.

Novel Fused N-Heterocycles Derived from 3,6-Dichloro-4-pyridazinecarbonyl Chloride

3,6-Dichloro-4-pyridazinecarbonyl chloride (4) reacts with primary amines to yield the N-containing fused heterocyclic compounds 2, 8, and 9a, b. 4 forms the pyridazino-oxadiazepines 7a-d with the in situ generated hydroxyguanidines 6a-d.The diazocinedione 1 is obtained by reaction of 3,6-dichloro-4-pyridazinecarboxamide (3) with anthranilic acid methyl ester.