51149-08-7

Usage

Uses

Used in Pharmaceutical Industry:
3,6-Dichloropyridazine-4-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its reactivity and functional groups allow for the creation of diverse drug candidates with potential therapeutic applications.
Used in Organic Synthesis:
3,6-Dichloropyridazine-4-carboxylic acid is used as a synthetic building block for the preparation of complex organic molecules. Its ability to undergo various chemical reactions, such as nucleophilic substitution and condensation, makes it a valuable component in the synthesis of advanced organic materials.
Used in the Synthesis of α-(halohetaroyl)-2-azahetarylacetonitriles:
3,6-Dichloropyridazine-4-carboxylic acid is used as a starting material for the synthesis of α-(halohetaroyl)-2-azahetarylacetonitriles. These compounds are of interest in the field of organic chemistry due to their potential applications in the development of new pharmaceuticals and other specialty chemicals.

InChI:InChI=1/C5H2Cl2N2O2/c6-3-1-2(5(10)11)4(7)9-8-3/h1H,(H,10,11)

Upstream product

• 19064-64-3 3,6-dichloro-4-methylpyridazine 

Downstream Products

• 34127-22-5 ethyl 3,6-dichloropyridazine-4-carboxylate 
• 100161-97-5 tert-butyl 3,6-dichloropyridazine-4-carboxylate 
• 6531-08-4 3,6-dichloropyridazine-5-carboxylic acid chloride 
• 955011-69-5 6-chloro-3-(2-fluoro-4-iodo-phenylamino)-pyridazine-4-carboxylic acid 
• 561297-99-2 3-(benzotriazol-1-yloxy)-6-chloro-pyridazine-4-carboxylic acid (4-tert-butyl-phenyl)-amide 
• 629651-96-3 3,6-dichloro-pyridazine-4-carboxylic acid (4-tert-butyl-phenyl)-amide 
• 686267-85-6 3-(benzylamino)-6-chloropyridazine-4-carboxylic acid 
• 50681-26-0 6-chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid 
• 286946-24-5 methyl 3,6-dichloropyridazine-4-carboxylate 
• 1416222-83-7 6-chloro-3-methyl-[1,2,4]triazolo[4,3-b]pyridazine-8-carboxylic acid 
• 1591827-16-5 methyl 6-chloro-3-methoxy-pyridazine-4-carboxylate 
• 89380-13-2 6-chloro-4-(chloromethyl)-3-methoxypyridazine 
• 1591827-79-0 3-chloro-5-((1-((6-chloro-3-methoxypyridazin-4-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 
• 1591827-87-0 3-chloro-5-((1-((3-methoxy-6-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)pyridazin-4-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile 

Relevant academic research and scientific papers

PYRIDAZINIL QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS

The invention concerns quinazoline derivatives of Formula (I) wherein Z is an O, S, SO, SO2, N(R2) or C(R2)(R3) group wherein each R2 or R3 group is hydrogen or (1-8C)alkyl, m is 1, 2 or 3, each R1 group has any of the meanings defined in the description, Ra is halogeno or (1-6C)alkoxy, Rb is halogeno or (1-6C)alkoxy, and Rc is hydrogen, halogeno, (1-8C)alkyl or (1-6C)alkoxy, or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.