27466-91-7

Upstream product

• 90-53-9 2,3-dimethoxyphenylacetic acid 
• 5424-43-1 3-bromoveratrole 
• 5764-82-9 bromo(2-ethoxy-2-oxoethyl)zinc 

Downstream Products

• 13335-51-8 2-(2,3-dimethoxyphenyl)ethan-1-ol 
• 200214-63-7 2-(2.3-Dimethoxyphenyl)-3-oxo-propionic Acid Ethylester 
• 101878-59-5 4-nitro-benzoic acid-(2,3-dimethoxy-phenethyl ester) 
• 709027-29-2 1-(2-bromo-ethyl)-2,3-dimethoxy-benzene 
• 84051-26-3 2-(2,3-Dimethoxy-phenyl)-N-{2-[2-hydroxy-3-(2-methylcarbamoylmethoxy-phenoxy)-propylamino]-ethyl}-acetamide 

Relevant academic research and scientific papers

Photoinduced Palladium-Catalyzed Negishi Cross-Couplings Enabled by the Visible-Light Absorption of Palladium–Zinc Complexes

A visible-light-induced Negishi cross-coupling is enabled by the activation of a Pd0–Zn complex. With this photocatalytic method, the scope of deactivated aryl halides that can be employed in the Negishi coupling was significantly expanded. NMR experiments conducted in the presence and absence of light confirmed that the formation of the palladium–zinc complex is key for accelerating the oxidative addition step.

AMINO ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS

There is provided compounds of formula I, wherein R 1, R 2, R 3, R x, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required as in thrombosis or as anticoagulants.