90-53-9

Basic information

• Product Name: 2,3-DIMETHOXYPHENYLACETIC ACID
• Synonyms: Acetic acid, (2,3-dimethoxyphenyl)-;Benzeneacetic acid, 2,3-dimethoxy-;RARECHEM AL BO 0333;2,3-DIMETHOXYPHENYLACETIC ACID;o-Homoveratric acid;2-(2,3-dimethoxyphenyl)acetic acid;2-(2,3-dimethoxyphenyl)ethanoic acid;2,3-DiMethoxybenzeneacetic Acid
• CAS NO: 90-53-9
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• Product Categories: Aromatics;Intermediates
• Mol File: 90-53-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 82-84°C
• Boiling Point: 235-240 C
• Flash Point: 123.9 °C
• Appearance: /
• Density: 1.189 g/cm³
• Vapor Pressure: 0.000154mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.03±0.10(Predicted)
• CAS DataBase Reference: 2,3-DIMETHOXYPHENYLACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIMETHOXYPHENYLACETIC ACID(90-53-9)
• EPA Substance Registry System: 2,3-DIMETHOXYPHENYLACETIC ACID(90-53-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-36-22
• Safety Statements: 26-36/37/39-36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 90-53-9(Hazardous Substances Data)

Usage

Uses

o-Homoveratric Acid is a metabolite of hydroxylated phenylalkylamines.

InChI:InChI=1/C10H12O4/c1-13-8-5-3-4-7(6-9(11)12)10(8)14-2/h3-5H,6H2,1-2H3,(H,11,12)

Upstream product

• 124-38-9 carbon dioxide 
• 4463-33-6 1,2-dimethoxy-3-methylbenzene 
• 19754-21-3 1-allyl-2,3-dimethoxy-benzene 
• 10028-15-6 ozone 
• 141-78-6 ethyl acetate 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 3893-01-4 2,3-dimethoxybenzyl chloride 
• 5653-67-8 2,3-dimethoxybenzyl alcohol 
• 99060-42-1 2-(2,3-dimethoxyphenyl)-2-hydroxyacetonitrile 
• 4468-57-9 2-(2,3-dimethoxyphenyl)acetonitrile 
• 19988-46-6 (2-hydroxy-3-methoxy-phenyl)-acetic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 796074-04-9 (2,3-dimethoxy-phenyl)-acetic acid-(2,3-dimethoxy-phenethylamide) 
• 59276-13-0 N-(3,4-dimethoxyphenethyl)-2,3-dimethoxyphenylacetamide 
• 54814-39-0 (E)-3-(3,4-Dimethoxy-phenyl)-2-(2,3-dimethoxy-phenyl)-acrylic acid 
• 27466-91-7 ethyl 2-(2,3-dimethoxyphenyl)acetate 
• 13335-51-8 2-(2,3-dimethoxyphenyl)ethan-1-ol 
• 5707-56-2 (2,3-dimethoxyphenyl)acetaldehyde 
• 1194473-25-0 C₁₄H₂₃O₅P 
• 69738-33-6 C₁₀H₁₃IO₂ 

Relevant articles and documents

PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES

[Problem] A problem is presented in that conventional photochromic compounds cannot be considered adequate in terms of the colorizing/decolorizing rate and durability, and the production process therefore has many steps. The present invention provides an industrially applicable photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability and can also be synthesized at a low cost. [Solution] This compound is characterized in that etheric oxygen atoms are bonded to the carbon atoms at position 1 of a pyranoquinazoline (8H-pyrano[3,2-f]quinazoline) skeleton and position 10 of a naphthopyran (3H-naphtho[2,1-b]pyran) skeleton, said compound having photochromic properties and being a photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability. Also provided is an industrially applicable photochromic compound that can be synthesized at a low cost.

An improved and versatile method for the rapid synthesis of aryldihydrobenzofuran systems by a boron tribromide-mediated cyclization reaction

Boron tribromide is presented as a highly reactive reagent that simultaneously allows the demethylation and fully diastereoselective cyclization of different precursor molecules, obtained by an aldol-type reaction, to a series of hydroxylated aryldihydrobenzofuran systems in racemic form. The latter are often found as key structures in natural compounds of different classes. Syntheses of educts, which mainly took advantage of a versatile Rieche formylation, are also described.

A convenient entry into the rhoeadan skeleton. Total synthesis of (±)-cis-alpinigenine

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