27490-76-2

Basic information

• Product Name: trimethyl-(4-methyl-phenethyl)-silane
• CAS NO: 27490-76-2
• Molecular Weight: 192.376
• Mol File: 27490-76-2.mol

Chemical Properties

• CAS DataBase Reference: trimethyl-(4-methyl-phenethyl)-silane(CAS DataBase Reference)
• NIST Chemistry Reference: trimethyl-(4-methyl-phenethyl)-silane(27490-76-2)
• EPA Substance Registry System: trimethyl-(4-methyl-phenethyl)-silane(27490-76-2)

Safety Data

• Hazardous Substances Data: 27490-76-2(Hazardous Substances Data)

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 1822-00-0 trimethylsilylmethyllithium 
• 4186-14-5 1-(2-(trimethylsilyl)ethynyl)toluene 
• 917-64-6 methyl magnesium iodide 
• 17964-79-3 trichloro(4-methylphenethyl)silane 

Downstream Products

• 27490-52-4 (3,3-Dichloro-2-p-tolyl-propyl)-trimethyl-silane 

Relevant articles and documents

Stereoselective one-pot synthesis of vinylsilanes from aromatic aldehydes

Vinylsilanes serve as convenient vinyl anion equivalents, but procedures for their stereoselective synthesis from aldehydes are scarce. A variety of aromatic aldehydes are converted to the corresponding vinylsilanes in a one-pot procedure involving the addition of (trimethylsilylmethyl)lithium to the aldehyde followed by treatment with Cp2TiCH2·AlMe2Cl ('Tebbe's reagent'). Halide and alkoxide substituents are tolerated, and (E)-vinylsilanes are formed exclusively in good yield.

Synthesis of (E)-alkenes via hydroindation of C{triple bond, long}C in InCl3-NaBH4 system

In InCl3-NaBH4-MeCN system, terminal aryl alkynes could couple with aryl iodides and bromides to give disubstituted alkenes via hydroindation of C{triple bond, long}C. In the similar way, (E)-alkenylsilanes were synthesized via reduction of alkynylsilanes in tetrahydrofuran (THF) in high yields. The processes showed high regio- and stereoselectivity.