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2757083-12-6

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2757083-12-6 Usage

General Description

The chemical compound (R)-N-((S)-(2-(di-tert-butylphosphanyl)phenyl)(phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide, is a sulfinamide derivative with the molecular formula C29H39NOSP and a molecular weight of 495.67 g/mol. It consists of a N,2-dimethylpropane-2-sulfinamide backbone connected to a (S)-(2-(di-tert-butylphosphanyl)phenyl)(phenyl)methyl) group. (R)-N-((S)-(2-(di-tert-butylphosphanyl)phenyl)(phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide is often utilized in the field of organic chemistry and drug synthesis due to its unique structure and potential pharmaceutical properties.

Check Digit Verification of cas no

The CAS Registry Mumber 2757083-12-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,7,5,7,0,8 and 3 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2757083-12:
(9*2)+(8*7)+(7*5)+(6*7)+(5*0)+(4*8)+(3*3)+(2*1)+(1*2)=196
196 % 10 = 6
So 2757083-12-6 is a valid CAS Registry Number.

2757083-12-6Downstream Products

2757083-12-6Relevant articles and documents

Design and Synthesis of TY-Phos and Application in Palladium-Catalyzed Enantioselective Fluoroarylation of gem-Difluoroalkenes

Li, Zhiming,Lin, Tao-Yan,Liu, Yu,Pan, Zhangjin,Tu, Youshao,Wu, Hai-Hong,Zhang, Junliang,Zhu, Shuai

supporting information, p. 22957 - 22962 (2020/10/19)

The first example of highly enantioselective fluoroarylation of gem-difluoroalkenes with aryl halides is presented by using a new chiral sulfinamide phosphine (Sadphos) type ligand TY-Phos. N-Me-TY-Phos can be easily synthesized on a gram scale from readily available starting materials in three steps. Salient features of this work including readily available starting materials, good yields, high enantioselectivities as well as broad substrate scope make this approach very practical and attractive. Notably, the asymmetric synthesis of an analogue of a biologically active molecule is also reported.

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