276238-73-4

Upstream product

• 212832-94-5 Methyl 3,4:5,6-di-O-isopropylidene-2-O-(benzyl)-D-gluconate 
• 1188522-27-1 1-morpholino-(2-O-benzyl-3,4:5,6-di-O-isopropylidene)-D-gluconamide 
• 100-39-0 benzyl bromide 
• 90-80-2 D-Glucono-1,5-lactone 
• 114743-85-0 methyl 3,4:5,6-di-O-isopropylidene-D-gluconate 

Downstream Products

• 639476-07-6 (2RS,4R,5S,6R,7R,8R)-N⁴-benzyl-N⁴-acetyl-1,5-bis(benzyloxy)-6,7:8,9-di-O-isopropylidenenonan-2-ol 
• 639476-08-7 (4R,5S,6R,7R,8R)-N⁴-benzyl-N⁴-acetyl-1,5-bis(benzyloxy)-6,7:8,9-di-O-isopropylidene-2-oxononane 
• 639476-10-1 N-benzyl-N-((2S,3R,5S,7R)-2-(benzyloxy)-5-((benzyloxy)methyl)-7-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-6,8-dioxabicyclo[3.2.1]octan-3-yl)acetamide 
• 639476-09-8 N-Benzyl-N-[(1R,2S,3R,5R,7R)-2-benzyloxy-5-benzyloxymethyl-7-((R)-1,2-dihydroxy-ethyl)-6,8-dioxa-bicyclo[3.2.1]oct-3-yl]-acetamide 
• 639476-06-5 (2RS,4R,5S,6R,7R,8R)-N⁴-benzyl-N⁴-acetyl-5-benzyloxy-6,7:8,9-di-O-isopropylidenenonane-1,2-diol 
• 639476-05-4 (4R,5S,6R,7R,8R)-N⁴-benzyl-N⁴-acetyl-5-benzyloxy-6,7:8,9-di-O-isopropylidene-1-nonene 
• 639476-04-3 (4R,5S,6R,7R,8R)-N⁴-benzyl-5-benzyloxy-6,7:8,9-di-O-isopropylidene-1-nonene 
• 639476-02-1 (R)-Benzyloxy-((4R,5S,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-acetaldehyde 

Relevant academic research and scientific papers

2-O-benzylation in D-gluconamide derivative under basic conditions with complete retention of stereo-integrity: Convenient access to 2-O-benzyl-3,4:5,6-di-O-isopropylidene-D-glucitol and other differently protected D-glucitol derivatives

A new and convenient synthesis of 2-O-benzyl-3, 4: 5, 6-di-O- isopropylidene-D-glucitol has been accomplished and has been generalized with the syntheses of differently protected D-glucitols at C-2 position. In the course of our new route to the different

Synthesis of a New Stable Conformationally Constrained 2,7-Anhydrosialic Acid Derivative

A stereoseletive synthesis of 2,7-anhydrosialic acid derivative 18 was achieved from D-glucono-δ-lactone. A highly syn-selective addition of Grignard reagent to the N-benzylimine 8 served as a key step.

Synthesis and application of N-methoxy-N-methyl-2-phenylsulfonyl- acetamide as a two-carbon homologating agent

With the well-known precedence that N-methoxy-N-methyl amides are excellent acyl cation and aldehyde equivalents, N-methoxy-N-methyl-2- phenylsulfonylacetamide (3), a new reagent, synthetically equivalent to ΘCH2CHO and ΘCH2COR was synthesised. The simplicity involved in the alkylation at the active methylene site in 3, followed by safe removal of the phenylsulfonyl group, makes 3 a versatile reagent for two-carbon homologation of alkyl halides. The method, when applied to sugar halides 6j and 6k led to the synthesis of 2,3-dideoxy sugars.