276248-85-2Relevant academic research and scientific papers
Synthesis of the apoptosis inducing agent apoptolidin. Assembly of the C(16)-C(28) fragment.
Sulikowski,Lee,Jin,Wu
, p. 1439 - 1442 (2000)
[reaction--see text] A stereoselective synthesis of the C(16)-C(28) fragment of the apoptosis inducing agent apoptolidin is described. Key steps include two propionate aldol reactions and a stereoselective Mukaiyama aldol addition of enolsilane 19 to beta
