27798-82-9

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 18278-29-0 1,5-bis(4-chlorophenyl)-1,4-pentadien-3-one 
• 30626-03-0 (3E)-4-(4-chlorophenyl)-3-buten-2-one 
• 18278-29-0 (1E,4E)-1,5-bis(4-chlorophenyl)-1,4-pentadiene-3-one 

Downstream Products

• 70071-32-8 r-2,cis-6-bis(p-chlorophenyl)-4-thianone oxime 
• 70071-36-2 (2R,4S,6S)-2,6-Bis-(4-chloro-phenyl)-tetrahydro-thiopyran-4-ylamine 
• 70095-68-0 (2R,4R,6S)-2,6-Bis-(4-chloro-phenyl)-tetrahydro-thiopyran-4-ylamine 

Relevant academic research and scientific papers

Spectral characterization and crystal structure of some 2,6-diarylthian-4-one hydrazone derivatives

A series of cis and trans 2,6-diarylthian-4-one hydrazone derivatives (11-16) have been synthesized and characterized by 1H, 13C and two dimensional NMR spectroscopy. For the 2r,6t-diphenylthian-4-one N-isonicotinoylhydrazone (14) X-ray diffraction have also been recorded. The coupling constants suggested that the cis-hydrazones (11-13), which have the phenyl groups in cis orientation, largely exist in chair conformations with equatorial orientation of the phenyl groups 11C. Analysis of the vicinal coupling constants of trans-hydrazones (14-16) suggests that boat forms 14B must make significant contributions to it and the relative population is 58%. Moreover, in solution chair conformations 14C and 14C′, may contribute to 14. The NOESY and X-ray diffraction of 14 gives definite evidence for the contribution of 14C.

Tetrahydrothiapyran-4,ones - Source for annelated 1,2,3- selena/thiadiazoles and their reactivity

1.2.3-Selenadiazole 4 and 1,2,3-thiadiazole 5 rings have been fused to 2.6-diaryl-(3-alkyl) tetrahydrothiapyran-4-ones 2 utilising α-ketomethylene group. The reactivity of the latter has also been studied viz., Beckmann rearrangement, Shapiro reaction. Strecker synthesis of α aminoacids etc.