2786-05-2

Basic information

• Product Name: DIBENZOFURAN-4-CARBOXYLIC ACID
• Synonyms: DIBENZOFURAN-4-CARBOXYLIC ACID;4-Dibenzofurancarboxylic acid;Dibenzofuran-4-carboxylic acid 97%;dibenzo[b,d]furan-4-carboxylic acid
• CAS NO: 2786-05-2
• Molecular Formula: C₁₃H₈O₃
• Molecular Weight: 212.2
• Product Categories: Benzofurans;Building Blocks;Heterocyclic Building Blocks;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 2786-05-2.mol

Chemical Properties

• Melting Point: 211-215 °C(lit.)
• Boiling Point: 425.7°Cat760mmHg
• Flash Point: 211.2°C
• Appearance: /
• Density: 1.387g/cm³
• Vapor Pressure: 5.26E-08mmHg at 25°C
• Refractive Index: 1.731
• Storage Temp.: 2-8°C
• PKA: 3.24±0.30(Predicted)
• CAS DataBase Reference: DIBENZOFURAN-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DIBENZOFURAN-4-CARBOXYLIC ACID(2786-05-2)
• EPA Substance Registry System: DIBENZOFURAN-4-CARBOXYLIC ACID(2786-05-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 2786-05-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
DIBENZOFURAN-4-CARBOXYLIC ACID is used as a building block for the synthesis of various biologically active compounds, contributing to the development of new pharmaceuticals and other organic compounds.
Used in Pharmaceutical Industry:
DIBENZOFURAN-4-CARBOXYLIC ACID is used as a key intermediate in the synthesis of pharmaceuticals, playing a crucial role in the production of drugs with potential therapeutic applications.
Used in Anti-inflammatory Applications:
DIBENZOFURAN-4-CARBOXYLIC ACID is used as an anti-inflammatory agent, potentially helping to reduce inflammation and associated symptoms in various conditions.
Used in Anti-cancer Applications:
DIBENZOFURAN-4-CARBOXYLIC ACID is used as an anti-cancer agent, being studied for its potential to inhibit the growth and progression of cancer cells.
Used in Enzyme Inhibition:
DIBENZOFURAN-4-CARBOXYLIC ACID is used to inhibit certain enzymes, which can be beneficial in the treatment of specific diseases and conditions.
Used in Electronic Materials Development:
DIBENZOFURAN-4-CARBOXYLIC ACID is used in the development of electronic materials, contributing to advancements in technology and electronics manufacturing.
Used in Photodynamic Therapy for Cancer Treatment:
DIBENZOFURAN-4-CARBOXYLIC ACID is being investigated for its potential use in photodynamic therapy, a cancer treatment method that uses a photosensitizing drug, light, and oxygen to kill tumor cells.

InChI:InChI=1/C13H8O3/c14-13(15)10-6-3-5-9-8-4-1-2-7-11(8)16-12(9)10/h1-7H,(H,14,15)

Upstream product

• 124-38-9 carbon dioxide 
• 74992-96-4 4-chlorodibenzo[b,d]furan 
• 51230-49-0 2-chlorodibenzofuran 
• 109-72-8 n-butyllithium 
• 26608-06-0 3-bromodibenzofuran 
• 60-29-7 diethyl ether 
• 71-43-2 benzene 

Downstream Products

• 92151-89-8 methyl dibenzo[b,d]furan-4-carboxylate 
• 295310-22-4 3-[5-dibenzofuran-4-ylcarbonylamino-2-methylphenyl]-6-(4-methylpiperazin-1-yl)-3,4-dihydroquinazolin-4-one 
• 170653-71-1 4,4-Diphenyl-1,4-dihydro-3,11-dioxa-1-aza-benzo[a]fluoren-2-one 
• 105478-98-6 p-bromophenacyl ester of 2-methyl-3-(4'-dibenzofuryl)propionic acid 
• 105478-98-6 (+)-2-methyl-3-(4'-dibenzofuryl)propionic acid p-bromophenacyl ester 
• 105479-03-6 p-nitrobenzyl ester of 2-methyl-3-(4'-dibenzofuryl)propionic acid 
• 105479-03-6 (+)-2-methyl-3-(4'-dibenzofuryl)propionic acid p-nitrobenzyl ester 
• 5410-97-9 3-nitrodibenzofuran 
• 263270-75-3 N-(3-amino-4-methylphenyl)dibenzofuran-4-carboxamide 
• 263270-73-1 N-(4-methyl-3-nitrophenyl)dibenzofuran-4-carboxamide 
• 86607-81-0 4-nitrodibenzo[b,d]furan 
• 1268162-33-9 dibenzo[b,d]furan-4-yldiphenylphosphine oxide 

Relevant articles and documents

Electrocarboxylation of chlorinated aromatic compounds

Chorinated benzenes (1, 4), biphenyls (6, 9), dibenzofurans (10, 15, 17, 18), 2-chlorodibenzo[1,4]dioxine (24) and 1-chloronaphthalene (26) as well as dibenzofuran (12) and naphthalene (27) themselves were transformed into carboxylic acids by galvanostatic electroreduction in the presence of carbon dioxide ("electrocarboxylation"). Dry DMF was used as solvent, zinc or stainless steel as cathode and magnesium as a sacrificial anode in an undivided cell. Hydrogenation of aromatic rings was not observed. However, reductive addition of two molecules of carbon dioxide to form dihydrodicarboxylic acids, e.g. 22 and 29, occurs in the dibenzofuran and naphthalene series.