278600-50-3

Basic information

• Product Name: 4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
• Synonyms: 4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine;[4-(3,4-dimethoxyphenyl)-2H-pyrazol-3-yl]amine;4-(3,4-dimethoxyphenyl)-2H-pyrazol-3-amine
• CAS NO: 278600-50-3
• Molecular Formula: C₁₁H₁₃N₃O₂
• Molecular Weight: 219.23982
• Mol File: 278600-50-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine(278600-50-3)
• EPA Substance Registry System: 4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine(278600-50-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 278600-50-3(Hazardous Substances Data)

Upstream product

• 93-17-4 3,4-dimethoxyphenylacetonitrile 
• 96729-80-5 2-(3,4-dimethoxyphenyl)-3-oxopropanenitrile 
• 93-03-8 (3,4-dimethoxyphenyl)methanol 
• 21852-32-4 4-bromomethyl-1,2-dimethoxybenzene 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 1084953-04-7 3-(3,4-dimethoxy-phenyl)-4H-pyrazolo[1,5-a]pyrimidin-5-one 
• 838855-36-0 4-[7,8-bis(methyloxy)-3H-pyrazolo[3,4-c]isoquinolin-5-yl]phenol trifluoroacetate 
• 1084951-40-5 (3-(4-(3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl)-2-methoxyphenoxy)propyl)carbamic acid tert-butyl ester 
• 1084951-41-6 3-(4-(3-(3,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-5-yl)-2-methoxyphenoxy)propylamine 
• 1015480-67-7 5-chloro-3-(3,4-dimethoxy-phenyl)-pyrazolo[1,5-a]pyrimidine 
• 921620-91-9 5-chloromethyl-6-(3-chloro-phenyl)-3-(3,4-dimethoxy-phenyl)-pyrazolo[1,5-a]pyrimidin-7-ylamine 
• 278600-54-7 8-(3,4-dimethoxy-phenyl)-2-methylsulfanyl-pyrazolo[1,5-a][1,3,5]triazin-4-ol 

Relevant articles and documents

PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL COMPOUNDS

A compound of formula (I) or a pharmaceutically acceptable salt thereof, useful in therapy, in particular in the treatment of a viral infection.

ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE

The present invention comprises compounds and pharmaceutical compositions comprising the compounds that are inhibitors of ALK. The invention also comprises methods of using the compounds and compositions to treat diseases mediated by ALK, including diseases such as cancer, immunological disorders, cardiovascular diseases, and other degenerative disorders.

PYRAZOLO[1,5-A]PYRIMIDIN-7-YL-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES

The invention relates to the use of pyrazolo[1,5a]pyrimidin-7-yl amine compounds and salts thereof in the treatment of kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases, novel pyrazolo[1,5a]pyrimidin-7-yl amine compounds, and a process for the preparation of the novel pyrazolo[1,5a]pyrimidin-7-yl amine compounds.