4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-amine

Base Information

Chemical Name:4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-amine
CAS No.:278600-50-3
Molecular Formula:C11H13N3O2
Molecular Weight:219.243
Hs Code.:2933199090
European Community (EC) Number:696-245-1
DSSTox Substance ID:DTXSID10353175
Wikidata:Q82130643
ChEMBL ID:CHEMBL1456790
Mol file:278600-50-3.mol

Synonyms:4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-amine;278600-50-3;4-(3,4-dimethoxyphenyl)-1H-pyrazol-3-amine;SMR000137610;Maybridge3_003486;Cambridge id 5118322;4-(3,4-Dimethoxy-phenyl)-2H-pyrazol-3-ylamine;Oprea1_194505;CBDivE_005086;MLS000532671;SCHEMBL1423967;CHEMBL1456790;DTXSID10353175;OZTPWGFELYCRFZ-UHFFFAOYSA-N;HMS1440O10;HMS2155A06;HMS3309H16;MFCD00454937;STL357559;AKOS002676120;AKOS015993670;CCG-250342;DG-0223;IDI1_014873;5-amino-4-(3,4-dimethoxyphenyl)pyrazole;CS-0313032;4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-ylamine;AB00074049-01;8T-0279

Suppliers and Price of 4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
1g
$ 252.00

Matrix Scientific
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
500mg
$ 219.00

Matrix Scientific
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
5g
$ 795.00

Crysdot
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine 95+%
5g
$ 752.00

Chemenu
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine 95%
5g
$ 711.00

Biosynth Carbosynth
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
2 g
$ 434.00

Biosynth Carbosynth
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
1 g
$ 255.00

Biosynth Carbosynth
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
5 g
$ 868.00

Biosynth Carbosynth
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
500 mg
$ 150.00

Biosynth Carbosynth
4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine
250 mg
$ 85.00

Total 5 raw suppliers

Chemical Property of 4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-amine

Chemical Property:

PSA：73.16000
LogP:2.25730
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:219.100776666
Heavy Atom Count:16
Complexity:227

Purity/Quality:

97% ^*data from raw suppliers

4-(3,4-Dimethoxyphenyl)-1H-pyrazol-5-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2=C(NN=C2)N)OC

Technology Process of 4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-amine

There total 6 articles about 4-(3,4-dimethoxyphenyl)-1H-pyrazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 96729-80-5
2-(3,4-dimethoxyphenyl)-3-oxopropanenitrile

: 278600-50-3
4-(3,4-dimethoxyphenyl)1H-pyrazol-5-amine

Guidance literature:: With hydrazine hydrochloride; acetic acid; In ethanol; at 85 ℃; Inert atmosphere;

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 109-94-4
formic acid ethyl ester

: 278600-50-3
4-(3,4-dimethoxyphenyl)1H-pyrazol-5-amine

Guidance literature:: 3,4-dimethoxyphenylacetonitrile; formic acid ethyl ester; With sodium methylate; In benzene; at 20 ℃; for 2h;

With acetic acid; hydrazine; In ethanol; for 6h; Heating;
DOI:10.1016/S0960-894X(00)00109-8

Reference yield:

: 21852-32-4
4-bromomethyl-1,2-dimethoxybenzene

: 278600-50-3
4-(3,4-dimethoxyphenyl)1H-pyrazol-5-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol; H₂O / 4 h / Heating

2.1: MeONa / benzene / 2 h / 20 °C

2.2: N₂H₄; AcOH / ethanol / 6 h / Heating

With sodium methylate; In ethanol; water; benzene; 1.1: Substitution / 2.1: Formylation / 2.2: Cyclization;
DOI:10.1016/S0960-894X(00)00109-8