2787-09-9Relevant articles and documents
Oxidant controlled regio- and stereodivergent azidohydroxylation of alkenes via I2 catalysis
Prasad,Reddi,Sudalai
, p. 10276 - 10279 (2015/06/25)
A novel, I2 catalyzed regio- and stereodivergent vicinal azidohydroxylation of alkenes leading to 1,2-azidoalcohols in high yields (up to 92%) and excellent dr (up to 98%) has been developed. This unprecedented transformation employs NaN3 and DMF as N- and O-nucleophiles respectively. The role of DMF as the O-source in the reaction has been unequivocally proven by 18O labelling studies.
Organocatalytic aziridine synthesis using F+ salts
Bew, Sean P.,Fairhurst, Shirley A.,Hughes, David L.,Legentil, Laurent,Liddle, John,Pesce, Paolo,Nigudkar, Sanket,Wilson, Martin A.
supporting information; experimental part, p. 4552 - 4555 (2009/12/05)
This paper describes a unique application of the fluoronium cation (F +) as an organocatalyst for mediating the reaction between N-substituted imines and ethyl diazoacetate affording excellent yields of N-substituted aziridines.
REGIOSELECTIVE ACYLATIVE CLEAVAGE OF CYCLIC FORMAL OF CHLORAMPHENICOL
Hazra, B. G.,Pore, V. S.,Maybhate, S. P.,Natekar, M. V.,Rao, A. S.
, p. 1763 - 1770 (2007/10/02)
The amide 6 has been synthesised by reacting the amine 3 with dichloroketene in situ.This amide 6 on nitration gave formal 7, which when reacted with acetic anhydride and p-toluene sulfonic acid underwent regioselective cleavage of the dioxane ring to furnish the hemiacetal 11.This on treatment with methanol-water-ammonia yielded chloramphenicol 2.