27886-67-5

Basic information

• Product Name: 5-ISO-BUTYL-5-METHYLHYDANTOIN
• Synonyms: 5-METHYL-5-(2-METHYLPROPYL)HYDANTOIN;5,5-METHYL-ISO-BUTYLHYDANTOIN;5-ISO-BUTYL-5-METHYLHYDANTOIN;5-ISOBUTYL-5-METHYLIMIDAZOLIDINE-2,4-DIONE;TIMTEC-BB SBB008139;5-Isobutyl-5-methyl-2,4-imidazolidinedione;5-Methyl-5-isobutylhydantoin;Hydantoin, 5-isobutyl-5-methyl-
• CAS NO: 27886-67-5
• Molecular Formula: C₈H₁₄N₂O₂
• Molecular Weight: 170.21
• Mol File: 27886-67-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 144.5 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.043g/cm³
• Refractive Index: 1.451
• PKA: 8.93±0.10(Predicted)
• CAS DataBase Reference: 5-ISO-BUTYL-5-METHYLHYDANTOIN(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ISO-BUTYL-5-METHYLHYDANTOIN(27886-67-5)
• EPA Substance Registry System: 5-ISO-BUTYL-5-METHYLHYDANTOIN(27886-67-5)

Safety Data

• Hazardous Substances Data: 27886-67-5(Hazardous Substances Data)

Usage

General Description

5-ISO-BUTYL-5-METHYLHYDANTOIN is a chemical compound that belongs to the class of hydantoins, which are cyclic compounds with a heterocyclic ring containing both nitrogen and oxygen atoms. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 5-ISO-BUTYL-5-METHYLHYDANTOIN is known for its antimicrobial properties and is often used as a preservative in various cosmetic and personal care products. Additionally, 5-ISO-BUTYL-5-METHYLHYDANTOIN has been studied for its potential use in the treatment of various medical conditions, including epilepsy and sleep disorders. However, it is important to handle this chemical with caution, as it may cause skin and eye irritation and should only be used in well-ventilated areas with proper personal protective equipment.

InChI:InChI=1/C8H14N2O2/c1-5(2)4-8(3)6(11)9-7(12)10-8/h5H,4H2,1-3H3,(H2,9,10,11,12)/t8-/m0/s1

Upstream product

• 506-87-6 ammonium carbonate 
• 108-10-1 4-methyl-2-pentanone 
• 7647-01-0 hydrogenchloride 
• 102539-40-2 4-isobutyl-4-methyl-5-thioxo-imidazolidin-2-one 
• 141-43-5 ethanolamine 
• 591-78-6 n-hexan-2-one 

Downstream Products

• 144-24-1 2-amino-2,4-dimethylpentanoic acid 
• 13893-50-0 2-amino-2,4-dimethyl-valeric acid ethyl ester 
• 102617-75-4 4-Isobutyl-4-methyl-2,5-dioxo-imidazolidine-1-carbonitrile 

Relevant articles and documents

Microwave-promoted facile and rapid synthesis procedure for the efficient synthesis of 5,5-disubstituted hydantoins

A fast, general, environmentally friendly, and facile method for preparation of 5, 5-disubstituted hydantoins from the reaction between ketone (or aldehyde) derivatives with KCN and ammonium carbonate under microwave irradiation is presented. The microwaves remarkably accelerated this reaction, the reaction times decreased dramatically, the reaction conditions were milder, and the yields were also greater. Also a comparative study of microwave versus classical conditions has been done. All the products were characterized by infrared, NMR, and CHN analysis, and their melting points are identical to those of the known compounds reported in the literature. This method might be useful in the future for the preparation of similar derivatives. Taylor & Francis Group, LLC.

Circular dichroism and configuration of alpha-amine acids

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