27909-08-6

Usage

Uses

Used in Pharmaceutical Industry:
(+)-4,4',7,7'-Tetramethoxy-5,5'-dimethyl-8,8'-bi(2H-1-benzopyran)-2,2'-dione is used as a pharmaceutical compound for its potential therapeutic properties. As a fungal metabolite, it may offer unique benefits in the development of new drugs and treatments, particularly in the areas of cancer research and other medical applications.
Used in Research and Development:
In the field of research and development, (+)-4,4',7,7'-Tetramethoxy-5,5'-dimethyl-8,8'-bi(2H-1-benzopyran)-2,2'-dione serves as a valuable compound for studying its chemical properties, structure, and potential interactions with biological systems. This knowledge can be applied to the design of new drugs, drug delivery systems, and other medical advancements.
Used in Chemical Synthesis:
(+)-4,4',7,7'-Tetramethoxy-5,5'-dimethyl-8,8'-bi(2H-1-benzopyran)-2,2'-dione can be utilized as a key intermediate or building block in the synthesis of more complex molecules and compounds. Its unique structure and properties make it a valuable asset in the development of new chemical entities with potential applications in various industries, including pharmaceuticals, materials science, and agriculture.
Used in Analytical Chemistry:
As a compound with distinct chemical and physical properties, (+)-4,4',7,7'-Tetramethoxy-5,5'-dimethyl-8,8'-bi(2H-1-benzopyran)-2,2'-dione can be employed in analytical chemistry for the development of new methods and techniques for the identification, quantification, and analysis of various substances. Its use in this field can contribute to advancements in quality control, environmental monitoring, and other analytical applications.

Upstream product

• 220482-16-6 (-)-(2R,3S)-1,4-bis(benzyloxy)-2-(2-bromo-3-methoxy-5-methylphenyl)oxy-3-t-butyldimethylsilyloxybutane 
• 220482-17-7 (-)-(2S,3R)-1,4-bis(benzyloxy)-3-(2-bromo-3-methoxy-5-methylphenyl)oxybutan-2-ol 
• 190844-48-5 Acetic acid 2'-acetoxy-6,6'-dimethoxy-4,4'-dimethyl-biphenyl-2-yl ester 
• 94429-22-8 3,3'-dimethoxy-5,5'-dimethyl-2,2'-biphenol 
• 27921-30-8 Carbonic acid 3,3'-diacetyl-6,6'-dimethoxy-2'-methoxycarbonyloxy-4,4'-dimethyl-biphenyl-2-yl ester methyl ester 
• 27909-13-3 (+)-2,2'-dihydroxy-3,3'-diacetyl-4,4'-dimethyl-6,6'-dimethoxybiphenyl 
• 36661-64-0 2-bromo-3-methoxy-5-methylphenol 
• 625838-65-5 (rac)-2,2'-diamino-7,7'-dimethoxy-5,5'-dimethyl-4H,4'H-8,8'-bichromene-4,4'-dione 
• 544423-38-3 (rac)-dimethyl 2,2'-dihydroxy-6,6'-dimethoxy-4,4'-dimethyl-1,1'-biphenyl-3,3'-dicarboxylate 
• 520-43-4 2-hydroxy-4-methoxy-6-methyl-benzoic acid methyl ester 
• 75-05-8 acetonitrile 
• 77-78-1 dimethyl sulfate 
• 190844-50-9 (rac)-4,4'-dihydroxy-7,7'-dimethoxy-5,5'-dimethyl-2H,2'H-8,8'-bichromene-2,2'-dione 

Relevant academic research and scientific papers

Unselective phenolic coupling of methyl 2-hydroxy-4-methoxy-6-methylbenzoate - A valuable tool for the total synthesis of natural product families

One monomeric orsellinate (1) suffices for a highly efficient total synthesis of the dimeric coumarins kotanin, isokotanin A, and desertorin C. The reason is the unselective course of its oxidative phenolic coupling, which leads to three regioisomeric biaryls as precursors of the dimers.

A short and efficient total synthesis of the naturally occurring coumarins siderin, kotanin, isokotanin A and desertorin C

Starting from methyl 2-hydroxy-4-methoxy-6-methyl-benzoate (6) and its regioisomeric dehydrodimers 7-9, readily available by an oxidative coupling reaction of 6, the naturally occurring coumarins siderin (1), kotanin (2), isokotanin A (3) and desertorin C (4) were synthesized in a novel and highly efficient three-step transformation. In the case of kotanin (2) both atropisomers were prepared from the pure atropisomers of 7.

The first asymmetric synthesis of the naturally occurring (+)-Kotanin and the assignment of its absolute configuration

The first asymmetric synthesis of the naturally occurring (+)-Kotanin is described. The key steps involve the intramolecular oxidative coupling of the cyanocuprate intermediate and the Fries rearrangement. The absolute configuration of (+)-Kotanin was assigned as aS by CD spectroscopic method.