279250-86-1Relevant articles and documents
2-ARYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS
-
Page/Page column 36, (2011/07/07)
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The pr
Synthesis, structure, and neuroprotective properties of novel imidazolyl nitrones
Dhainaut, Alain,Tizot, André,Raimbaud, Eric,Lockhart, Brian,Lestage, Pierre,Goldstein, Solo
, p. 2165 - 2175 (2007/10/03)
A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This connectivi