27927-59-9

Basic information

• Product Name: 1-Pentanone,4-hydroxy-1-phenyl-
• Synonyms: Valerophenone,4-hydroxy- (8CI)
• CAS NO: 27927-59-9
• Molecular Formula: C11H14 O2
• Molecular Weight: 178.231
• Mol File: 27927-59-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 1-Pentanone,4-hydroxy-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanone,4-hydroxy-1-phenyl-(27927-59-9)
• EPA Substance Registry System: 1-Pentanone,4-hydroxy-1-phenyl-(27927-59-9)

Safety Data

• Hazardous Substances Data: 27927-59-9(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 861399-10-2 (RS)-1-(n-butyltellanyl)-3-butanol 
• 583-05-1 1-phenylpentane-1,4-dione 
• 89968-81-0 1-Phenylpentane-1,4-diol 
• 1228681-29-5 1-phenyl-2-pentene-1,4-diol 
• 132205-09-5 (1R*,2Z,4S*)/(1R*,2Z,4R*)-1-Phenyl-2-pentene-1,4-diol 
• 64-17-5 ethanol 
• 768-03-6 Phenyl vinyl ketone 
• 1713-41-3 trans-1-Phenyl-2-methylcyclobutanol 
• 16330-23-7 1-phenyl-1-pentyn-4-ol 
• 613-91-2 acetophenone oxime 
• 1008-76-0 4,5-dihydro-5-phenyl-2(3H)-furanone 
• 98-86-2 acetophenone 
• 75-56-9 methyloxirane 

Downstream Products

• 164113-08-0 2-ethylthio-2-methyl-5-phenyltetrahydrofuran 
• 4457-59-4 (2R*,5S*)-2-methyl-5-phenyltetrahydrofuran 
• 2235-83-8 5-phenyl-2-pentanone 
• 583-05-1 1-phenylpentane-1,4-dione 

Relevant articles and documents

Identification of Bond-Weakening Spirosilane Catalyst for Photoredox α-C?H Alkylation of Alcohols

The development of catalyst-controlled site-selective C(sp3)?H functionalization is a current major challenge in organic synthesis. This paper describes DFT-guided identification of pentavalent silicate species as a novel bond-weakening catalyst for the α-C?H bonds of alcohols together with a photoredox catalyst and a hydrogen atom transfer catalyst. Specifically, Martin's spirosilane accelerated α-C?H alkylation of alcohols. (Figure presented.).

Mutual Cooperation in the Formal Allyl Alcohol Nucleophilic Substitution and Hydration of Alkynes for the Construction of γ-Substituted Ketones

Mutual cooperation in the formal allyl alcohol nucleophilic substitution reaction and hydration of an alkyne has been utilized in the presence of a gold catalyst to give a series of γ-functionalized ketones with high to excellent yields. This reaction actually involved an intramolecular O-H insertion cyclization of an alkyne to form the dihydrofuran intermediate, which was followed by the nucleophilic addition ring-opening of a dihydrofuran to give the target compound.

A facile preparation of tetralins from arene-1,4-diones using titanium(IV) chloride and triethylsilane

A facile method for the synthesis of tetralins has been described which uses various substituted phenylpentane-1,4-diones as starting material with a combination of TiCl4/Et3SiH. The synthesis involves three reactions under mild conditions. A mechanism has been proposed for the reductive cyclization through ionic hydrogenation, and titanium(IV) chloride catalyzed cyclization.