27948-26-1

Basic information

• Product Name: 5-PHENYL-PENT-2-EN-4-YNOIC ACID METHYL ESTER
• Synonyms: 5-PHENYL-PENT-2-EN-4-YNOIC ACID METHYL ESTER
• CAS NO: 27948-26-1
• Molecular Formula: C₁₂H₁₀O₂
• Molecular Weight: 186.2066
• Mol File: 27948-26-1.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 278.8±32.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 5-PHENYL-PENT-2-EN-4-YNOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PHENYL-PENT-2-EN-4-YNOIC ACID METHYL ESTER(27948-26-1)
• EPA Substance Registry System: 5-PHENYL-PENT-2-EN-4-YNOIC ACID METHYL ESTER(27948-26-1)

Safety Data

• Hazardous Substances Data: 27948-26-1(Hazardous Substances Data)

Upstream product

• 6214-22-8 methyl (Z)-3-bromoacrylate 
• 536-74-3 phenylacetylene 
• 6213-88-3 3-iodoacrylic acid methyl ester 
• 412304-80-4 methyl 5-phenylpenta-2,4-diynoate 
• 6214-23-9 methyl (2Z)-3-iodoprop-2-enoate 
• 1085-51-4 bis(2-phenylethynyl)zinc 
• 922-67-8 propynoic acid methyl ester 

Downstream Products

• 344340-95-0 5-iodo-6-phenyl-2(2H)-pyranone 
• 129593-48-2 (Z)-5-phenyl-2-penten-4-yn-1-ol 
• 30625-92-4 (Z)-5-phenylpent-2-en-4-ynal 
• 2689-59-0 (furan-2-yl)(phenyl)methanone 
• 30625-91-3 (E)-5-phenylpent-2-en-4-ynal 

Relevant articles and documents

Phosphine-Mediated [4 + 3] Annulation of Diynoates and 2-Arylidene Indane-1,3-diones: Access of Indeno[1,2- b]oxepin-4-ylidenes and beyond

A novel unprecedented triphenylphosphine-mediated [4 + 3] annulation reaction of 2-benzylidene indane-1,3-diones and -diynoates through initial phosphine α-addition was discovered and found to result in biologically interesting indeno[1,2-b]oxepin-4-ylidenes in up to 75% yield. The seven-membered separable Z and E isomeric oxepins were confirmed using single-crystal X-ray diffraction.

Palladium-Catalyzed One-Pot Highly Regioselective 6- Endo Cyclization and Alkylation of Enynoates: Synthesis of 2-Alkanone Pyrones

The Pd(II)-catalyzed one-pot tandem cyclization/alkylation reactions of enynoates with allylic alcohols have been demonstrated. In this reaction, an innovative protocol proceeded well through Pd-catalyzed intramolecular selective 6-endo cyclization, inser

Stoichiometric and Catalytic C?C and C?H Bond Formation with B(C6F5)3 via Cationic Intermediates

This work showcases a new catalytic cyclization reaction using a highly Lewis acidic borane with concomitant C?H or C?C bond formation. The activation of alkyne-containing substrates with B(C6F5)3 enabled the first catalytic intramolecular cyclizations of carboxylic acid substrates using this Lewis acid. In addition, intramolecular cyclizations of esters enable C?C bond formation as catalytic B(C6F5)3 can be used to effect formal 1,5-alkyl migrations from the ester functional groups to unsaturated carbon–carbon frameworks. This metal-free method was used for the catalytic formation of complex dihydropyrones and isocoumarins in very good yields under relatively mild conditions with excellent atom efficiency.