6213-88-3

Basic information

• Product Name: methyl (E)-3-iodoprop-2-enoate
• Synonyms: (2E)-3-Iodoprop-2-enoic acid methyl ester;-Methyl 3-iodoacrylate;methyl (E)-3-iodoprop-2-enoate;(E)-Methyl 3-iodoacrylate
• CAS NO: 6213-88-3
• Molecular Formula: C₄H₅IO₂
• Molecular Weight: 211.99
• Mol File: 6213-88-3.mol
• Article Data: 21

Chemical Properties

• Melting Point: 84-85℃
• Boiling Point: 182℃
• Flash Point: 64℃
• Appearance: /
• Density: 1.918
• Vapor Pressure: 0.823mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: methyl (E)-3-iodoprop-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (E)-3-iodoprop-2-enoate(6213-88-3)
• EPA Substance Registry System: methyl (E)-3-iodoprop-2-enoate(6213-88-3)

Safety Data

• Hazardous Substances Data: 6213-88-3(Hazardous Substances Data)

Usage

General Description

Methyl (E)-3-iodoprop-2-enoate is an organic compound with the chemical formula C4H5IO2. It is a colorless to pale yellow liquid that is commonly used as a reagent in organic synthesis. methyl (E)-3-iodoprop-2-enoate is commonly used in the preparation of various organic compounds and is also used as a building block in the production of pharmaceuticals and agrochemicals. Methyl (E)-3-iodoprop-2-enoate is a highly reactive compound and should be handled with care in a well-ventilated area and with appropriate safety precautions.

InChI:InChI=1/C4H5IO2/c1-7-4(6)2-3-5/h2-3H,1H3/b3-2+

Upstream product

• 922-67-8 propynoic acid methyl ester 
• 6214-23-9 methyl (2Z)-3-iodoprop-2-enoate 
• 67-56-1 methanol 
• 6372-02-7 (E)-3-iodoacrylic acid 
• 82101-74-4 methyl (E)-3-(tributylstannyl)acrylate 
• 6214-35-3 (Z)-3-iodoprop-2-enoic acid 
• 186581-53-3 diazomethane 

Downstream Products

• 2271-21-8 methyl (E)-5-(thiophen-2-yl)pent-2-en-4-ynoate 
• 49833-37-6 (E)-methyl 3-thiophenyl-2-propenoate 
• 181263-03-6 (E)-(S)-5-[(2R,4aR,6R,7S,8S,8aR)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl]-4-hydroxy-pent-2-enoic acid methyl ester 
• 187840-84-2 methyl (E)-3-(diisopropylphenylsilyl)propenoate 
• 88761-82-4 methyl β-(E)-2-dimethylphenylsilylacrylate 
• 312709-29-8 (E)-6-{(1R,2R)-1-tert-Butoxycarbonylamino-2-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-cyclopentyl}-hex-2-enoic acid methyl ester 
• 56015-01-1 methyl 4-hydroxy-4-phenyl-(E)-but-2-enoate 
• 516472-44-9 methyl (E)-4-cyclohexyl-4-hydroxybut-2-enoate 
• 500795-21-1 methyl-(2E,4E,6S,7S,8R,9S)-4,6-dimethyl-6,9-O-methylidene-8-(E-2'-methyl-3'-trimethylsilanyl-2'-enyl)-7-p-methoxybenzyloxy-tetradeca-2,4-dienoate 
• 1208610-09-6 methyl 4-propyl-6-phenylhex-3(Z)-5-ynoate 
• 1220117-28-1 methyl (2E,4R)-4-hydroxy-4-{(1R,2S,4S)-2-{(E)-6-[(4-methoxybenzyl)oxy]hex-1-enyl}-4-(methoxymethoxy)cyclopentyl}but-2-enoate 
• 1220117-29-2 methyl (2E,4S)-4-hydroxy-4-{(1R,2S,4S)-2-{(E)-6-[(4-methoxybenzyl)oxy]hex-1-enyl}-4-(methoxymethoxy)cyclopentyl}but-2-enoate 
• 103-26-4 methyl cinnamate 
• 1263054-20-1 C₁₃H₁₂O₂ 

Relevant articles and documents

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Enantioselective Synthesis of α-Chiral Propargylic Silanes by Copper-Catalyzed 1,4-Selective Addition of Silicon Nucleophiles to Enyne-Type α,β,γ,δ-Unsaturated Acceptors

A copper-catalyzed deconjugative addition of silicon nucleophiles to a broad range of enyne-type α,β,γ,δ-unsaturated acceptors with high enantiocontrol is reported. The method is 1,4-selective with hardly any formation of the 1,6-adduct. The double-bond geometry is shown to be critical for achieving this chemoselectivity: exclusive 1,4-addition for E and predominant 1,6-addition for Z. By this, E-configured enynoates, enynamides, and enynones have been converted to the corresponding α-chiral propargylic silanes with excellent enantiomeric excesses.