27957-91-1

Usage

Uses

Used in Organic Synthesis:
1-Methyl-L-proline methyl ester serves as a key intermediate in organic synthesis, facilitating the creation of a variety of complex organic molecules. Its presence in reactions can lead to the formation of new compounds with potential applications across different industries.
Used in Pharmaceutical Research:
In the pharmaceutical sector, 1-Methyl-L-proline methyl ester is utilized as a building block for the synthesis of biologically active molecules and pharmaceutical drugs. Its incorporation into drug development processes can contribute to the creation of novel medications designed to treat a range of diseases and conditions.
Used in Medication Development:
1-Methyl-L-proline methyl ester holds promise in the development of new medications, particularly due to its potential to be integrated into the structures of therapeutic agents. Its unique structural attributes make it a candidate for enhancing the efficacy and selectivity of drugs targeting specific conditions.

Upstream product

• 186581-53-3 diazomethane 
• 147-85-3 L-proline 
• 67-56-1 methanol 

Downstream Products

• 34381-71-0 (S)-2-hydroxymethyl-1-methylpyrrolidine 
• 852324-29-9 (S)-N-methylpyrrolidine-2-carboxaldehyde 
• 250672-60-7 (S)-(-)-3-(N-methylpyrrolidin-2-ylcarbonyl)-4-benzyloxyindole 
• 181359-58-0 (7R,8R,8aS)-5-Oxo-8-phenylselanyl-octahydro-indolizine-7-carboxylic acid ethyl ester 
• 147402-53-7 (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole 
• 173521-73-8 (S)-2-(3-aminobut-2-enoyl)-N-methylpyrrolidine 

Relevant academic research and scientific papers

Synthesis of new mono- and bisorganophosphorus proline derivatives with P–C–N moieties

The various methods of aminomethylation of some PH-acids with proline and their derivatives are investigated. The numerous derivatives of proline and corresponding phosphonates, phosphonites, phosphinates, and phosphorane with proline moieties are presented.

Synthesis of mono-and diphosphorus-substituted proline derivatives containing P–C–N fragments

Convenient methods for the synthesis of new types of mono-and diphosphorus-substituted proline derivatives containing P–C–N fragments were developed based on special pre-prepared proline-containing synthons. The corresponding organophosphorus acids including a proline fragment were also synthesized.

SYNTHESIS OF SOME SILICON- AND PHOSPHORUS-SUBSTITUTED DERIVATIVES OF PROLINE

On the basis of L-proline methyl ester its N-substituted derivatives were obtained, which included an alkoxymethyl, trimethylsilyl, or diethoxyphosphinomethyl group.The reaction of proline methyl ester with paraform results in bismethane.The latter was used for synthesis of a phosphinate containing two fragments of proline by double aminomethylation of bis(trimethylsiloxy)phosphine.