27974-01-2

Basic information

• Product Name: Benzeneethanamine, N-(2-phenylethyl)-N-propyl-
• CAS NO: 27974-01-2
• Molecular Formula: C19H25N
• Molecular Weight: 267.414
• Mol File: 27974-01-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzeneethanamine, N-(2-phenylethyl)-N-propyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanamine, N-(2-phenylethyl)-N-propyl-(27974-01-2)
• EPA Substance Registry System: Benzeneethanamine, N-(2-phenylethyl)-N-propyl-(27974-01-2)

Safety Data

• Hazardous Substances Data: 27974-01-2(Hazardous Substances Data)

Upstream product

• 27906-91-8 N-propyl-2-phenylethylamine 
• 622-24-2 2-phenylethyl chloride 
• 71-23-8 propan-1-ol 
• 64-04-0 phenethylamine 
• 103-80-0 phenylacetyl chloride 
• 100-42-5 styrene 
• 107-10-8 propylamine 
• 103-63-9 1-phenyl-2-bromoethane 

Relevant articles and documents

Ruthenium-catalyzed N-alkylation of amines with alcohols under mild conditions using the borrowing hydrogen methodology

Using a simple amino amide ligand, ruthenium-catalyzed one-pot alkylation of primary and secondary amines with simple alcohols was carried out under a wide range of conditions. Using the alcohol as solvent, alkylation was achieved under mild conditions, even as low as room temperature. Reactions occurred with high conversion and selectivity in many cases. Reactions can also be carried out at high temperatures in organic solvent with high selectivity using stoichiometric amounts of the alcohol.

D2 Dopaminergic and 5-HT1A Serotonergic Activity of 2-(1-Naphthyl)ethyl- and 2-(2-Naphthyl)ethyl Amines

Several tertiary 2-phenylethyl, 2-(1-naphthyl)ethyl and 2-(2-naphthyl) ethyl amines were synthesized and their binding affinities for dopamine D 1, D2 and serotonin 5-HT1A receptors evaluated in radioligand binding assays.