27975-48-0Relevant academic research and scientific papers
Novel compound capable of activating Nrf2, and pharmaceutical compositions comprising the same
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Paragraph 0082-0086, (2016/10/08)
The present invention provides a novel compound which can activate Nrf2 that is a transcription factor for expression of the quinone reductase gene. Therefore the compound is effective for inhibiting apoptosis and preventing and treating brain nerve disea
Synthesis of multi-substituted cyclobutanes and alkylidenecyclobutanes by the reaction of cyclobutylmagnesium carbenoids with nucleophiles
Satoh, Tsuyoshi,Kasuya, Takashi,Ishigaki, Masashi,Inumaru, Mio,Miyagawa, Toshifumi,Nakaya, Nobuhito,Sugiyama, Shimpei
experimental part, p. 397 - 408 (2011/04/15)
Treatment of 1-chlorocyclobutyl p-tolyl sulfoxides with Grignard reagents such as ethylmagnesium chloride, isopropylmagnesium chloride, and cyclopentylmagnesium chloride in THF at low temperature gave cyclobutylmagnesium carbenoids in high yields. The gen
