280-13-7 Usage
General Description
8-Oxa-3-azabicyclo[3.2.1]octane, also known as oxabicyclooctane or OBO, is a bicyclic organic compound containing a heterocyclic oxygen and nitrogen atom. It is a colorless liquid with a pleasant odor, and is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. OBO has a unique molecular structure that allows it to serve as a versatile intermediate in organic chemistry reactions, such as in the formation of heterocyclic compounds and chiral ligands. Its stable and non-reactive nature, combined with its ability to serve as a chiral building block, make it a valuable molecule in the field of organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 280-13-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,8 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 280-13:
(5*2)+(4*8)+(3*0)+(2*1)+(1*3)=47
47 % 10 = 7
So 280-13-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO/c1-2-6-4-7-3-5(1)8-6/h5-7H,1-4H2
280-13-7Relevant articles and documents
Novel route for the synthesis of 8-oxa-3-azabicyclo[3.2.1]octane: One-pot aminocyclization of 2,5-tetrahydrofurandimethanol catalyzed by Pt/NiCuAlOx
Cui, Xinjiang,Yuan, Hangkong,Li, Jerry-Peng,De Campo, Floryan,Pera-Titus, Marc,Deng, Youquan,Shi, Feng
, p. 195 - 199 (2015)
2,5-Tetrahydrofurandimethanol (THFDM) was selectively transformed into 8-oxa-3-azabicyclo[3.2.1] octane (OABCO), a valuable building block for the synthesis of bioactive molecules, via one-pot aminocyclization with ammonia catalyzed by Pt/NiCuAlOx. Under optimized conditions (200 °C, 6-16 h, 0.5 MPa hydrogen, 0.4 MPa ammonia), the OABCO yield reached 58% with 100% THFDM conversion.
Substituted benzothiazole amide derivatives
-
, (2008/06/13)
A compound of formula I and a method of treatment of diseases, related to modulation of the adenosine A2 receptor system comprising administering a compound of formula 1to a person in need of such treatment.
