28047-23-6

Basic information

• Product Name: Benzene, (chlorocyclohexylmethyl)-
• CAS NO: 28047-23-6
• Molecular Formula: C13H17Cl
• Molecular Weight: 208.731
• Mol File: 28047-23-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzene, (chlorocyclohexylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (chlorocyclohexylmethyl)-(28047-23-6)
• EPA Substance Registry System: Benzene, (chlorocyclohexylmethyl)-(28047-23-6)

Safety Data

• Hazardous Substances Data: 28047-23-6(Hazardous Substances Data)

Upstream product

• 945-49-3 cyclohexylphenylmethanol 
• 945-49-3 (S)-cyclohexylphenylmethanol 
• 110-82-7 cyclohexane 
• 74670-99-8 3-Chlor-3-phenyl-1,2-diaziridin 
• 36140-19-9 dicyclohexylboron chloride 
• 100-52-7 benzaldehyde 
• 39105-81-2 (dichloro)(cyclohexyl)borane 
• 712-50-5 Cyclohexyl phenyl ketone 
• 2043-61-0 cyclohexanecarbaldehyde 
• 110-83-8 cyclohexene 

Downstream Products

• 101866-04-0 1-(cyclohexyl-phenyl-methyl)-pyrrolidine 
• 102019-53-4 1-ethyl-4-(cyclohexyl-phenyl-methyl)-piperazine 
• 1351371-83-9 4-(cyclohexylphenylmethoxy)piperidine 
• 1351373-28-8 ethyl 4-(cyclohexylphenylmethoxy)piperidine-1-carboxylate 
• 945-49-3 (S)-cyclohexylphenylmethanol 
• 945-49-3 (R)-cyclohexylphenylmethanol 
• 1197002-74-6 C₂₈H₂₉FO₃ 
• 101872-44-0 1-(cyclohexyl-phenyl-methyl)-4-methyl-piperazine 

Relevant articles and documents

Ferric chloride–catalyzed deoxygenative chlorination of carbonyl compounds: A comparison of chlorodimethylsilane and dichloromethylsilane system

Deoxygenative chlorination of carbonyl compounds using the HMe2SiCl/FeCl3/EtOAc and HMeSiCl2/FeCl3/EtOAc systems has been systemically investigated. The HMe2SiCl-FeCl3 system showed the advantages of good substrate applicability, mild reaction conditions, simple operation, low cost, and easy availability of raw materials. Also, it provided a simple and efficient synthesis route for carbonyl deoxychlorination via a one-pot method. Using the HMeSiCl2/FeCl3/EtOAc system, the β-methylchalcone derivative could be obtained in good yields in addition to obtaining the chlorinated compound. Finally, two plausible reaction routes were proposed to describe the formation of the chlorinated compound and the β-methylchalcone derivative.

Intermolecular Pummerer Coupling with Carbon Nucleophiles in Non-Electrophilic Media

A new Pummerer-type C?C coupling protocol is introduced based on turbo-organomagnesium amides, which unlike traditional Pummerer reactions, does not require strong electrophilic activators, engages a broad range of C(sp3)-, C(sp2)-, and C(sp)-nucleophiles, and seamlessly integrates with C?H and C?X magnesiation. Given the central character of sulfur compounds in organic chemistry, this protocol allows access to unrelated carbonyls, olefins, organometallics, halides, and boronic esters through a single strategy.

HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST

A heterocyclic compound useful as an antiallergic agent is provided. A compound represented by the following formula (1) or a salt thereof: wherein the ring A is a homocyclic or heterocyclic ring; the ring B is a heterocyclic ring which contains G and nitrogen atom N as constituent atoms thereof, wherein G is CH or N; R1 is a carbonyl group or an alkylene group; R2a and R2b are an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group; X is an oxygen atom or a sulfur atom; Z is a hydroxyl group, an alkoxy group, a cycloalkyloxy group, an aryloxy group, an aralkyloxy group, an amino group, or an N-substituted amino group; and n is 0 or 1; with the proviso that when the ring A is a benzene ring or when the ring B is a piperazine ring, R1 is an alkylene group which may have a substituent.