28048-29-5

Usage

Uses

Used in Chemical Synthesis:
(2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is used as a key intermediate in the synthesis of various organic compounds. Its reactivity and functional groups make it suitable for use in a wide range of chemical reactions, including esterification, amidation, and condensation reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is used as a building block for the development of new drugs. Its unique structure and properties allow it to be incorporated into the design of novel therapeutic agents, potentially leading to the discovery of new treatments for various diseases and conditions.
Used in Research and Development:
(2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is also utilized in research and development settings, where it can be employed to study the properties and behavior of various chemical compounds. Its reactivity and functional groups make it an ideal candidate for use in experiments and investigations aimed at understanding the fundamental principles of organic chemistry.
Used in Material Science:
In the field of material science, (2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER can be used to develop new materials with unique properties. Its incorporation into polymers, coatings, and other materials can lead to the creation of innovative products with enhanced performance characteristics.

InChI:InChI=1/C11H9NO4/c1-2-16-11(13)8-7-9-5-3-4-6-10(9)12(14)15/h3-6H,2H2,1H3

Upstream product

• 64-17-5 ethanol 
• 530-85-8 3-(2-nitrophenyl)-2-propynoic acid 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 66700-63-8 diethyl 1-iodo-1-carbethoxy-methylphosphonate 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 866155-18-2 ethyl 3-(p-tolyl)-1H-indole-2-carboxylate 
• 1246775-33-6 ethyl 3-(4-bromophenyl)-1H-indole-2-carboxylate 
• 158072-90-3 ethyl 3-(4-methoxyphenyl)-1H-indole-2-carboxylate 
• 1296130-05-6 C₁₈H₁₇NO₃ 
• 1296130-06-7 C₁₇H₁₄INO₂ 
• 1296130-07-8 C₂₀H₁₉NO₄ 
• 1296130-11-4 C₂₄H₂₁NO₃ 
• 1296130-12-5 C₂₅H₁₉NO₂ 
• 37129-23-0 ethyl 3-phenyl-1H-indole-2-carboxylate 
• 93957-39-2 3-(4-Fluorophenyl)-1H-indole-2-carboxylic acid,ethyl ester 

Relevant academic research and scientific papers

trans Deformation of a Carbon-Carbon Triple Bond in Response to Incipient Nucleophilic Attack: the X-Ray Crystal Structure of Ethyl 3-(2-Nitrophenyl)propynoate at 150 K

In the title compound 1 the electron-deficient alkyne bond shows a pronounced trans distortion in response to an adjacent electron rich nitro O atom, suggesting that the more favourable reaction coordinate for addition of nucleophiles to activated alkynes involves trans rather than cis addition.

The reaction of substituted ethyl α-bromocinnamates with tetrabutyl ammonium fluoride

The reaction of ethyl α-bromocinnamates with tetrabutyl ammonium fluoride (TBAF) was influenced largely by the position of the substituent at the phenyl ring. While the substrates without an ortho substituent at the phenyl ring were transformed to the cor

Synthesis of 3-arylindole-2-carboxylates via copper-catalyzed hydroarylation of o-nitrophenyl-substituted alkynoates and subsequent cadogan cyclization

A two-step route to biologically important 3-arylindole-2-carboxylic esters has been successfully established: o-nitrophenyl-substituted alkynoates underwent copper-catalyzed hydroarylation in the presence of commercially available arylboronic acids to afford 3,3-diarylacrylates, which were then converted to indolecarboxylates via a modified Cadogan cyclization using a molybdenum catalyst and triphenylphosphine. Copyright

Preparation of α-bromoacrylates: One-pot procedure for the synthesis of conjugated acetylenic carboxylates from aldehydes with Ph3P/ Br3CCO2Et

We have established the optimal conditions for the Wittig reaction for synthesizing α-bromoacrylates with a high selectivity, and developed a simple and efficient one-pot procedure for preparing various conjugated acetylenic carboxylates in moderate to high yields. Georg Thieme Verlag Stuttgart.