28080-54-8 Usage
General Description
6-Iodo-3-nitropyridine is a chemical compound with the molecular formula C5H3IN2O2. This organic compound belongs to the class of organic compounds known as iodo pyridines, characterized by a pyridine ring substituted by one iodine atom. It is used as a key intermediate in the production of many pharmaceuticals and agrochemicals. Its physical appearance is a pale yellow crystalline powder. It should be noted that this chemical requires careful handling due to its reactivity and potential health risks associated with exposure. Its properties allow it to be used in a wide range of chemical reactions in the pharmaceutical industry, showcasing its importance in synthesis processes.
Check Digit Verification of cas no
The CAS Registry Mumber 28080-54-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,8 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 28080-54:
(7*2)+(6*8)+(5*0)+(4*8)+(3*0)+(2*5)+(1*4)=108
108 % 10 = 8
So 28080-54-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H3IN2O2/c6-5-2-1-4(3-7-5)8(9)10/h1-3H
28080-54-8Relevant articles and documents
-
Reinheimer et al.
, p. 2770,2771 (1962)
-
Synthesis and cardiac imaging of 18F-ligands selective for β1-adrenoreceptors
Radeke, Heike S.,Purohit, Ajay,Harris, Thomas D.,Hanson, Kelley,Jones, Reinaldo,Hu, Carol,Yalamanchili, Padmaja,Hayes, Megan,Yu, Ming,Guaraldi, Mary,Kagan, Mikhail,Azure, Michael,Cdebaca, Michael,Robinson, Simon,Casebier, David
supporting information; experimental part, p. 650 - 655 (2011/11/05)
A series of potent and selective β1-adrenoreceptor ligands were identified (IC50 range, 0.04-0.25 nM; β1/ β2 selectivity range, 65-450-fold), labeled with the PET radioisotope fluorine-18 and evaluated in normal Sprague-Dawley rats. Tissue distribution studies demonstrated uptake of each radiotracers from the blood pool into the myocardium (0.48-0.62% ID/g), lung (0.63-0.97% ID/g), and liver (1.03-1.14% ID/g). Dynamic μPET imaging confirmed the in vivo dissection studies.
