28081-31-4

Basic information

• Product Name: Dimethylnitrosuccinate
• Synonyms: Dimethylnitrosuccinate
• CAS NO: 28081-31-4
• Molecular Formula: C₆H₉NO₆
• Molecular Weight: 189.12288
• Mol File: 28081-31-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Dimethylnitrosuccinate(CAS DataBase Reference)
• NIST Chemistry Reference: Dimethylnitrosuccinate(28081-31-4)
• EPA Substance Registry System: Dimethylnitrosuccinate(28081-31-4)

Safety Data

• Hazardous Substances Data: 28081-31-4(Hazardous Substances Data)

Upstream product

• 2483-57-0 methyl 2-nitroacetate 
• 96-32-2 bromoacetic acid methyl ester 
• 40149-67-5 dimethyl aspartate 
• 10420-33-4 dimethyl 2-acetylsuccinate 
• 760-90-7 dimethyl 2-bromosuccinate 
• 98298-19-2 3-bromo-4-methoxy-4-oxobutanoic acid 

Downstream Products

• 40149-67-5 dimethyl aspartate 

Relevant articles and documents

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Synthesis of α-Nitro Carbonyls via Nitrations in Flow

Reported is a safe, rapid method for the synthesis of α-nitro esters via the trapping of nitronium ions. The two-stage nitration and subsequent deacetylation of readily available 1,3-dicarbonyl compounds was achieved using a biphasic semicontinuous approach. α-Nitro esters and amides were obtained in good overall yields (53-84%). Some of the α-nitro-1,3-dicarbonyl intermediates exhibit enhanced reactivity and undergo an acid-catalyzed Nef-type reaction to α-oxo-carbonyls.

CARBON-CARBON BOND FORMATION BY MEANS OF SUBSTITUTION AND ADDITION REACTIONS INVOLVING THE POLYMER-SUPPORTED CARBANION FROM METHYL NITROACETATE

A polymer-supported carbanion has been prepared from methyl nitroacetate and reacted with alkyl halides or activated olefins to give α-nitroesters.