28095-56-9

Basic information

• Product Name: DL-3-(1-NAPHTHYL)ALANINE
• Synonyms: alpha-Amino-1-naphthalenepropanoic acid;DL-alpha-amino-1-naphthalenepropionic acid;3-(1-Naphthyl);3-(1-Naphthyl)-DL-alanine99+%;DL-3-Ala(1-naphthyl)-OH;2-AMINO-3-NAPHTHALEN-1-YL-PROPIONIC ACID;3-(1-NAPHTHYL)-DL-ALANINE;BETA-1-NAPHTHYL ALANINE
• CAS NO: 28095-56-9
• Molecular Formula: C₁₃H₁₃NO₂
• Molecular Weight: 215.25
• Product Categories: Amino Acids;I - Z;Modified Amino Acids
• Mol File: 28095-56-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 239℃
• Boiling Point: 412.3 °C at 760 mmHg
• Flash Point: 203.2 °C
• Appearance: /
• Density: 1.254
• Vapor Pressure: 1.54E-07mmHg at 25°C
• Refractive Index: 1.66
• Storage Temp.: 2-8°C
• PKA: 2.21±0.30(Predicted)
• CAS DataBase Reference: DL-3-(1-NAPHTHYL)ALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: DL-3-(1-NAPHTHYL)ALANINE(28095-56-9)
• EPA Substance Registry System: DL-3-(1-NAPHTHYL)ALANINE(28095-56-9)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 28095-56-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 23, p. 4255, 1982 DOI: 10.1016/S0040-4039(00)88718-3

InChI:InChI=1/C13H13NO2/c14-12(13(15)16)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7,12H,8,14H2,(H,15,16)

Upstream product

• 102241-41-8 5-[1]naphthylmethylene-3-p-tolyl-imidazolidine-2,4-dione 
• 59759-78-3 2-benzoylamino-3-naphthalen-1-yl-propionic acid 
• 157521-32-9 acetylamino-[1]naphthylmethyl-malonic acid 
• 86-52-2 1-Chloromethylnaphthalene 
• 939-26-4 2-bromomethylnaphthyl bromide 
• 10034-85-2 hydrogen iodide 
• 5440-57-3 diethyl (N-acetylamino)[(1-naphthyl)methyl]malonate 
• 144754-21-2 2-benzoylamino-3-[1]naphthyl-acrylic acid 
• 61442-33-9 5-naphthalen-1-ylmethylene-2-thioxo-3-p-tolyl-imidazolidin-4-one 
• 125700-36-9 2-Amino-3-naphthalen-1-yl-propionic acid ethyl ester; hydrochloride 
• 59759-53-4 DL-N-Benzoyl-η-1-naphthyl-alaninamid 
• 143218-06-8 2-acetylamino-2-cyano-3-[1]naphthyl-propionic acid ethyl ester 
• 57427-83-5 4-naphthalen-1-ylmethylene-2-phenyl-4H-oxazol-5-one 
• 66-77-3 1-naphthaldehyde 

Downstream Products

• 123760-85-0 2-(4-Chloro-benzylamino)-3-naphthalen-1-yl-propionic acid 
• 176036-48-9 Nα-fluorenylmethyloxycarbonyl-DL-1-naphthylalanine 
• 108327-31-7 α-(((Phenylmethoxy)carbonyl)amino)-1-naphthalenepropanoic acid 
• 62741-58-6 3-(naphthalene-1-yl)-2-oxopropanoic acid 
• 55516-54-6 L-1-naphthylalanine 
• 136375-70-7 naphythylalanine methylester 
• 78306-92-0 3-(1-naphthyl)-D-alanine 

Relevant articles and documents

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SUBSTITUTED AZEPINONE DUAL INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME AND NEUTRAL EXDOPEPTIDASE

Compounds of the formula STR1 are disclosed as possessing inhibitory activity against angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP) and thus being useful as cardiovascular agents. Processes for preparing these compounds are also disclosed.

TRANSITION METAL COMPLEXES - A NEW CLASS OF CATALYSTS OF INTERFACIAL ALKYLATION FOR THE ASYMMETRICAL SYNTHESIS OF α-AMINO ACIDS

A new class of catalysts of interfacial asymmetrical alkylation is suggested for the synthesis of α-amino acids - positively charged complexes of the transition metals Cu(II), Ni(II), and Pd(II).These complexes consist of several fragments, by variation of which the structure of the catalysts can readily be modified.The complexes are chiral on account of (S)proline derivatives contained in them as one of the fragments.The catalyst complexes (C) were used in alkylation of amino acid fragments of Ni(II) complexes of the Schiff base of glycine with N-(2-pyridinecarbonyl)-o-aminobenzophenone (Ni-PBP-Gly) and the Schiff base of alanine with N-(2-pyridinecarbonyl)-o-aminobenzaldehyde (Ni-PBA-Ala) under interfacial conditions.After decomposition of alkylated complexes, phenylalanine and α-methyl-phenylalanine were isolated with yields of 33-87percent and optical purity (o. p.) from 3 to 21percent, depending on the C used.