281190-96-3

Upstream product

• 2243-53-0 trans-styrylacetic acid 
• 175523-35-0 (+)-(1R,2S)-1-(N-tosylamino)-2-indanol 

Downstream Products

• 162465-18-1 (S)-2-((R)-3-Amino-2-methyl-propionyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-1-carboxy-2-(4-methoxy-phenyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester 
• 728944-93-2 (2S,1''S,2''R,1''''R)-1''-[3'''-({1''''-[(tert-butoxy)carbonyl]-2''''-(p-methoxyphenyl)ethyl}carbamoyl)allyl]-2''-methyl-4''-phenylbut-3''-enyl 2-[(3'-{[(tert-butoxy)carbonyl]amino}propionyl)oxy]-4-methylpentanoate 
• 281191-03-5 (2S,2'R,1''S,2''R,1''''R)1''-(3'''-{1''''-[(tert-butoxy)carbonyl]-2''''-p-methoxyphenylethylcarbamoyl}allyl)-2''-methyl-4''-phenylbut-3''-enyl 2-[(3'-{[(tert-butoxy)carbonyl]amino}-2'-methylpropionyl)oxy]-4-methylpentanoate 
• 281191-01-3 (2R,2'E,5'S,6'R,7'E)-tert-butyl 3-(4-methoxyphenyl)-2-({6'-methyl-8'-phenyl-5'-[(triisopropylsilanyl)oxy]octa-2',7'-dienoyl}amino)propionate 
• 281191-02-4 (2R,2'E,5'S,6'R,7'E)-tert-butyl 2-[(5'-hydroxy-6'-methyl-8'-phenylocta-2',7'-dienoyl)amino]-3-(4-methoxyphenyl)propionate 
• 281190-99-6 (1S,2R,3E)-({1-[2'-(benzyloxy)ethyl]-2-methyl-4-phenylbut-3-enyl}oxy)triisopropylsilane 
• 281191-00-2 (2E,5S,6R,7E)-ethyl 6-methyl-8-phenyl-5-[(triisopropylsilanyl)oxy]octa-2,7-dienoate 
• 281190-94-1 (2E,5S,6R,7E)-6-methyl-8-phenyl-5-[(triisopropylsilanyl)oxy]octa-2,7-dienoic acid 
• 281191-04-6 (3S,4R,5E)-4-methyl-6-phenyl-3-[(triisopropylsilanyl)oxy]hex-5-en-1-ol 
• 728944-90-9 (2S,3S)-5-(benzyloxy)-2-[(E)-styryl]pentane-1,3-diol 
• 281191-05-7 (3S,4R,5E)-4-methyl-6-phenyl-3-[(triisopropylsilanyl)oxy]hex-5-enal 
• 281190-98-5 (3S,4R,5E)-1-(benzyloxy)-4-methyl-6-phenylhex-5-en-3-ol 
• 162600-54-6 cryptophycin-24 
• 162473-78-1 desepoxyarenastatin A 

Relevant academic research and scientific papers

A convergent synthesis of (+)-cryptophycin B, a potent antitumor macrolide from Nostoc sp. cyanobacteria.

[structure--see text] An efficient and highly stereoselective synthesis of cryptophycin B (2), a potent cytotoxic agent, is described. The ester-derived titanium-enolate-mediated syn-aldol reaction was employed to generate the stereocenters C(5) and C(6). The route is convergent and provides a convenient access to the synthesis of structural variants of cryptophycin B as well as members of its family.