28170-90-3

Basic information

• Product Name: 1,3-bis(isothiocyanatomethyl)benzene
• Synonyms: benzene, 1,3-bis(isothiocyanatomethyl)-
• CAS NO: 28170-90-3
• Molecular Formula: C₁₀H₈N₂S₂
• Molecular Weight: 220.3139
• Mol File: 28170-90-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 371.2°C at 760 mmHg
• Flash Point: 189.5°C
• Density: 1.14g/cm³
• Vapor Pressure: 2.24E-05mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: 1,3-bis(isothiocyanatomethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(isothiocyanatomethyl)benzene(28170-90-3)
• EPA Substance Registry System: 1,3-bis(isothiocyanatomethyl)benzene(28170-90-3)

Safety Data

• Hazardous Substances Data: 28170-90-3(Hazardous Substances Data)

Usage

General Description

1,3-bis(isothiocyanatomethyl)benzene is a chemical compound with the molecular formula C12H10N2S2. It is a benzene derivative that contains two isothiocyanatomethyl groups attached to the 1 and 3 positions of the benzene ring. 1,3-bis(isothiocyanatomethyl)benzene is commonly used in organic synthesis and as a reagent in chemical reactions due to its ability to crosslink with proteins and other molecules. It has potential applications in the development of drugs, polymers, and materials due to its unique chemical properties. Additionally, 1,3-bis(isothiocyanatomethyl)benzene is known for its strong and pungent odor, and it should be handled with caution due to its irritant and toxic properties.

Upstream product

• 75-15-0 carbon disulfide 
• 1477-55-0 1,3-di(aminomethyl)benzene 
• 6160-65-2 1,1'-Thiocarbonyldiimidazole 
• 539-48-0 p-xylylidenediamine 
• 108-45-2 m-phenylenediamine 
• 463-71-8 thiophosgene 
• 16801-19-7 2-[2-(vinyloxy)ethoxymethyl]oxirane 

Downstream Products

• 329771-57-5 1,3-bis[3-[4-(tert-butoxycarbonylaminomethyl)benzyl]thioureidomethyl]benzene 
• 1416702-88-9 1,1'-(1,3-phenylenebis(methylene))bis(3-((S)-1-phenylethyl)thiourea) 
• 329771-58-6 1,3-bis[3-[4-(aminomethyl)benzyl]thioureidomethyl]benzene 
• 442636-26-2 C₅₀H₅₆N₈O₂S₆ 

Relevant articles and documents

Multi-stimuli controlled release of a transmembrane chloride ion carrier from a sulfonium-linked procarrier

In recent times, anion transporters have received substantial consideration due to their ability to disrupt the ionic equilibrium across membrane bilayers. While numerous Cl- ion transporters were developed for channelopathies, unfortunately, poor aqueous solubility precluded their bioapplicability. Herein, we demonstrate the development of a multi-stimuli activatable anion transport approach to induce regulated transport of Cl- ions across membranes under specific conditions. The sulfonium-based procarrier was initially inactive, but the transmembrane transport of Cl- ions was activated in the presence of stimuli such as glutathione (GSH), reactive oxygen species (ROS) and light. The release of the hydrophobic anionophore from the aqueous-soluble procarrier under specific conditions leads to the successful transport of Cl- ions. Under physiological conditions, these anion carriers follow an antiport exchange mechanism to transport Cl- ions across lipid bilayers. Such multi-stimuli activatable procarriers have great potential to combat various types of channelopathies, including cancer, cystic fibrosis, kidney stones, myotonia, and others.

A sulfur key Lian Niao multifunctional synergistic antioxidant stabilizer preparation method

The invention relates to a preparation method of a multi-functional synergetic anti-oxidative stabilizer for sulfide bond linked urea. The preparation method comprises the following steps: (1) adding organic amine into CS2 and alkali to react; adding meth

Synthesis and biological activity of novel symmetrical bis-2- phenyliminothiazolidine derivatives

A series of novel symmetrical bis-2-phenyliminothiazolidine derivatives were designed and synthesized. The structures of all the title compounds were characterized by 1H NMR and, in some cases, by 13C NMR, IR, and high-resolution mas