28191-82-4

Upstream product

• 1956-39-4 (E)-1-(4-chlorophenyl)ethanone oxime 
• 140-88-5 ethyl acrylate 

Downstream Products

• 119881-37-7 (6R,7R)-3-Acetoxymethyl-7-{3-[1-(4-chloro-phenyl)-eth-(E)-ylideneaminooxy]-propionylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 119881-32-2 (6R,7R)-7-{3-[1-(4-Chloro-phenyl)-eth-(E)-ylideneaminooxy]-propionylamino}-3-methyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 63564-50-1 α-methyl-4-chlorobenzylideneaminoxy propionic acid 

Relevant academic research and scientific papers

Synthesis, antiinflammatory activity and platelet anti-aggregating activity of a new series of β-aminoxypropionic acids

A series of β-aminoxypropionic acids (AOPAs) had previously been designed and synthesised as analogues of antiinflammatory arylacetic acids (ArAAs) in which the Ar portion is substituted by the (methyleneaminoxy) methyl moiety (O = NOCH2, MAOMM

Synthesis and antimicrobial properties of substituted β-aminoxypropionyl penicillins and cephalosporins

Some β-aminoxypropionyl penicillins (3) and cephalosporins (4 and 5), planned on the basis of the hypothesis that the (methyleneaminoxy)methyl group (>C = NOCH2) could be a 'bioisoster' of either aryls or other aromatic groups, were synthesized and assayed for their antimicrobial properties. Compounds 3-5, tested on Gram-positive and Gram-negative bacteria, both sensitive to enzyme inactivation and otherwise, exhibited an activity trend that was not substantially different from that of the corresponding phenylacetamido derivatives taken as terms of comparison.