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2-[(1-amino-4-carboxy-1-oxobutan-2-yl)carbamoyl]benzoic acid, also known as 5-aminosalicylic acid (5-ASA), is a chemical compound with the molecular formula C7H7NO4. It is a derivative of salicylic acid and is commonly used in the treatment of inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease. 5-ASA works by reducing inflammation in the gastrointestinal tract and has anti-inflammatory and immunomodulatory properties. It is available in various forms, including oral tablets, suppositories, and enemas, and is often used as a first-line therapy for mild to moderate cases of inflammatory bowel disease.

2820-44-2

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2820-44-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2820-44-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,2 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2820-44:
(6*2)+(5*8)+(4*2)+(3*0)+(2*4)+(1*4)=72
72 % 10 = 2
So 2820-44-2 is a valid CAS Registry Number.

2820-44-2Downstream Products

2820-44-2Relevant academic research and scientific papers

Hydrolyzed metabolites of thalidomide: Synthesis and TNF-α production-inhibitory activity

Nakamura, Takanori,Noguchi, Tomomi,Miyachi, Hiroyuki,Hashimoto, Yuichi

, p. 651 - 654 (2008/02/08)

Putative hydrolyzed metabolites of thalidomide were prepared and characterized, and their inhibitory activity on tumor necrosis factor (TNF)-α production in the human monocytic leukemia cell line THP-1 was evaluated. α-(2-Carboxybenzamido)glutarimide was a more potent TNF-α production inhibitor than thalidomide.

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