28222-02-8

Basic information

• Product Name: 5-nitro-2-phenoxypyridine
• Synonyms: 5-nitro-2-phenoxypyridine
• CAS NO: 28222-02-8
• Molecular Formula: C₁₁H₈N₂O₃
• Molecular Weight: 216
• Mol File: 28222-02-8.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-nitro-2-phenoxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-nitro-2-phenoxypyridine(28222-02-8)
• EPA Substance Registry System: 5-nitro-2-phenoxypyridine(28222-02-8)

Safety Data

• Hazardous Substances Data: 28222-02-8(Hazardous Substances Data)

Upstream product

• 4548-45-2 2-chloro-5-nitropyridine 
• 108-95-2 phenol 
• 3229-70-7 phenolate 
• 66923-86-2 sodium phenoxide trihydrate 
• 4487-59-6 2-bromo-5-nitropyridine 
• 139-02-6 sodium phenoxide 

Downstream Products

• 5446-92-4 2-methoxy-5-nitropyridine 
• 1051942-43-8 1H-indole-3-carboxylic acid (6-phenoxy-pyridin-3-yl)-amide 
• 26820-54-2 2-butylamino-5-nitropyridine 
• 26820-61-1 5-nitro-2-piperidinopyridine 
• 25194-67-6 6-phenoxy-pyridin-3-ylamine 
• 118420-45-4 (E)-N-[4-(4-Benzhydryl-piperazin-1-yl)-butyl]-3-(6-phenoxy-pyridin-3-yl)-acrylamide 
• 118420-05-6 (E)-3-(6-phenoxy-pyridin-3-yl)-acrylic acid 
• 332008-89-6 N-(6-phenoxypyridin-3-yl)benzamide 
• 595576-50-4 N-(6-phenoxypyridin-3-yl)acetamide 
• 352018-92-9 5-iodo-2-phenoxypyridine 
• 595576-43-5 5-fluoro-2-phenoxypyridine 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY

The present invention provides a novel heterocyclic compound represented by Formula [I] and a salt thereof: wherein the symbols are as defined in the specification, which is useful for treating, preventing and/or diagnosing seizure and the like in disease involving epileptic seizure or convulsive seizure (including multiple drug resistant seizure, refractory seizure, acute symptomatic seizure, febrile seizure and status epilepticus), as well as a medical use therefor.

INHIBITORS OF BRUTON'S TYROSINE KINASE

This application discloses compounds according to generic Formula (I): wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are useful for the treatment of oncological, auto-immune, and inflammatory diseases caused by aberrant B-cell activation. Also disclosed are compositions containing compounds of Formula I and at least one carrier, diluent or excipient.

Novel indol carboxylic acid bispyridyl carboxamide derivatives as 5-HT2c receptor antagonists

Disclosed herein are a new indole carboxylic acid bispyridyl carboxamide derivative, a preparation method thereof, and a composition for prevention or treatment of obesity, urinary disorders, and CNS disorders, containing the same as an active ingredient. Because the indole carboxylic acid bispyridyl carboxamide derivatives according to the present invention have high affinity for 5-HT2c receptors, act selectively on the 5-HT2c receptors, the derivatives rarely have adverse effects caused by other receptors. Because the derivatives effectively inhibit serotonin activity, they may be useful for treatment or prevention of obesity; urinary disorders such as urinary incontinence, premature ejaculation, erectile dysfunction, and prostatic hyperplasia; CNS disorders such as depression, anxiety, concern, panic disorder, epilepsy, obsessive-compulsive disorder, migraine, sleep disorder, withdrawal from drug abuse, Alzheimer's disease, and schizophrenia, associated with 5-HT2c receptors.