2827-18-1

Upstream product

• 542-85-8 Ethyl isothiocyanate 
• 106-49-0 p-toluidine 
• 75-04-7 ethylamine 
• 622-59-3 1-isothiocyanato-4-methylbenzene 

Downstream Products

• 1096570-88-5 C₂₄H₂₂N₂S 
• 1096570-85-2 C₁₉H₂₀N₂S 
• 1170007-04-1 1-ethyl-2-isopropyl-3-p-tolylisothiourea 
• 61449-47-6 2,4-diethyl-3,5-bis(4-methylphenylimino)-1,2,4-thiadiazolidine 
• 55695-44-8 (3-amino-4-p-tolyl-4H-[1,2,4]thiadiazol-5-ylidene)-ethyl-amine 
• 85063-61-2 N-ethyl-6-methylbenzo[d]thiazol-2-amine 

Relevant academic research and scientific papers

Synthesis, characterization and structural study of new ethyl thiourea compounds and the preliminary naked-eye sensors for mercury and argentum metal ions

Novel ethyl thiourea compounds 1a- 1f have been synthesized in good to high yields. The structure of all compounds were identified using FT-IR, 1H NMR, 13C NMR spectroscopies, and ESI-Mass spectrometry. The compound 1-ethyl-3-(3-meth

Anion transport across varying lipid membranes - The effect of lipophilicity

The anion transport properties of a range of alkyl-substituted phenylthioureas were tested in vesicles of different lipid composition. Although changes in the bilayer affected the rate of transport for all compounds in the series, the 'ideal' log P for pe

Synthesis of thiazolidines via regioselective addition of unsymmetric thioureas to maleic acid derivatives

A wide range of unsymmetric thioureas has been studied in reaction with N-arylmaleimides and maleic anhydride. The regioselectivity of the addition depends not only on steric factors but on both solvent polarity and type of maleic acid derivative (imide o

Synthesis of phenylisothiourea derivatives as inhibitors of NO production in LPS activated macrophages

A series of phenylisothioureas were synthesized as inhibitors of NO production in lipopolysaccharide-activated macrophages. We investigated the effect of lipophilic moiety and N- or S-substituents of the phenylisothioureas on the activity. Inhibitory acti

A convenient one-pot three component approach to synthesis of highly substituted iminothiazolines

An efficient one-pot three component method was developed for the synthesis of highly substituted 2-iminothizolines by the reaction of isothiocyanates, primary amines and α-bromoketones in ambient temperature. The reaction produced the desired products in a completely regioselective manner in excellent yields (78-94%). The Japan Institute of Heterocyclic Chemistry.

COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE

Compounds of formula (I), and salts and solvates thereof for use as a medicament are provided: (I) wherein R1, R2, R4, R10, X and Z are defined in the specification. Processes for preparation, pharmaceutical com

Structure and hydrogen bonding of solid N1-alkyl-N2-arylthioureas. 13C CP/MAS, IR and semi-empirical AM1 studies

Seven crystalline N1-alkyl-N2-arylthioureas were studied by 13C CP/MAS NMR and by IR spectroscopy. The double set of signals in 13C CP/MAS spectra indicates that molecules of N1-ethyl-N2-(3-methylphenyl)thiourea and N1-ethyl-N2-(4-methylphenyl)thiourea are crystallographically non-equivalent. N1-Propene-N1-phenylthiourea forms cyclic dimers with two N2-H...S hydrogen bonds, as confirmed recently by x-ray diffraction. The broad vNH maxima at 3175-3295 cm-1 in the IR spectra indicate that in other thioureas both N1-H and N2-H protons are involved in hydrogen bonding and that the non-bonded N1-H proton in cyclic dimers of N1-propenethioureas is probably an exception. Semi-empirical AM1 calculations showed that the N2-H proton is more positively charged than the N1-H proton and therefore should be preferentially involved in N2-H...S hydrogen bonds.