85063-61-2Relevant academic research and scientific papers
Synthesis of 2-aminobenzothiazole via FeCl3-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water
Ding, Qiuping,Cao, Banpeng,Liu, Xianjin,Zong, Zhenzhen,Peng, Yi-Yuan
supporting information; experimental part, p. 1607 - 1610 (2010/12/19)
An FeCl3-catalyzed tandem reaction of 2-iodoaniline with isothiocyanate in water is described, which provides an environmentally benign, efficient, and practical route for the generation of 2-aminobenzothiazole. This present tandem process shows broad substrate scope in the presence of octadecyltrimethylammonium chloride as a phase-transfer catalyst. In addition, the reaction media can be recovered and recycled without loss of efficiency.
