2827-56-7

Basic information

• Product Name: 1-Aminohydantoin hydrochloride
• Synonyms: TIMTEC-BB SBB004061;1-AMINO-IMIDAZOLIDINE-2,4-DIONE HYDROCHLORIDE;1-AMINOHYDANTOIN HCL;1-AMINOHYDANTOIN HYDROCHLORIDE;1-AMINO-2,4-IMIDAZOLIDINEDIONE HCL;1-AMINO-2,4-IMIDAZOLIDIONE HCL;1-Amino-2,4-Imidazolinedione;1-Aminoimidazoline-2,4-dione hydrochloride
• CAS NO: 2827-56-7
• Molecular Formula: C3H6ClN3O2
• Molecular Weight: 151.55
• Product Categories: Chemical Amines;Amines;Heterocycles;Building Blocks;Heterocyclic Building Blocks;Imidazolines/Imidazolidines;A;Alphabetic;AM to AQ;Metabolites & Impurities;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Pharmaceutical intermediates;Amines, Heterocycles, Metabolites & Impurities
• Mol File: 2827-56-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 201-205 °C(lit.)
• Boiling Point: 256.8 °C at 760 mmHg
• Flash Point: 109.1 °C
• Appearance: Pale yellow/Crystalline Powder
• Vapor Pressure: 0.0119mmHg at 25°C
• Storage Temp.: 0-6°C
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• Stability: Unstable in Solution
• BRN: 3699376
• CAS DataBase Reference: 1-Aminohydantoin hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Aminohydantoin hydrochloride(2827-56-7)
• EPA Substance Registry System: 1-Aminohydantoin hydrochloride(2827-56-7)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 2827-56-7(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Powder

Uses

Different sources of media describe the Uses of 2827-56-7 differently. You can refer to the following data:
1. A metabolite of Nitrofuran.
2. Reactant for synthesis of: Ectoparasiticidal drugs1 Skeletal muscle relaxants2Reactant for: Suzuki-Miyaura coupling3 Lymphoid specific tryosine phosphatase inhibitor4 Proteasome inhibition by peptide semicarbazones5
3. 1-Aminohydantoin hydrochloride may be used as one of the reactants in the synthesis of (E)-1-(2-hydroxybenzylideneamino)imidazolidine-2,4-dione, dantrolene and dantrolene sodium.

InChI:InChI=1/C3H5N3O2.ClH/c4-6-1-2(7)5-3(6)8;/h1,4H2,(H,5,7,8);1H

Upstream product

• 67-20-9 Nitrofurantoin 

Downstream Products

• 623145-57-3 1-(2-nitrobenzylideneamino)hydantoin 
• 49622-72-2 1-((2,4-dihydroxybenzylidene)amino)imidazolidine-2,4-dione 
• 2827-57-8 1-[(2-phenylmethylene)amino]-2,4-imidazolidinedione 
• 67-20-9 Dantafur 
• 7261-97-4 1-[[[5-(4-nitrophenyl)-2-furanyl]methylene]imino]-2,4-imidazolidinedione 
• 833480-90-3 dantrolene 
• 67-20-9 Nitrofurantoin 
• 14663-26-4 1-[5-(4-chloro-phenyl)-furan-2-ylmethyleneamino]-imidazolidine-2,4-dione 

Relevant articles and documents

Plant Uptake and Metabolism of Nitrofuran Antibiotics in Spring Onion Grown in Nitrofuran-Contaminated Soil

Environmental pollution caused by the discharge of mutagenic and carcinogenic nitrofurans to the aquatic and soil environment is an emerging public health concern because of the potential in producing drug-resistant microbes and being uptaken by food crops. Using liquid chromatography-tandem mass spectrometry analysis and with spring onion (Allium wakegi Araki) as the plant model, we investigated in this study the plant uptake and accumulation of nitrofuran from a contaminated environment. Our study revealed for the first time high uptake and accumulation rates of nitrofuran in the edible parts of the food crop. Furthermore, results indicated highly efficient plant metabolism of the absorbed nitrofuran within the plant, leading to the formation of genotoxic hydrazine-containing metabolites. The results from this study may disclose a previously unidentified human exposure pathway through contaminated food crops.