623145-57-3

Basic information

• Product Name: 2-NP-AHD
• Synonyms: 1-(2-nitrobenzylidenamino)-2,4-imidazolidinedione;NP-AHD;1-[[(2-Nitrophenyl)Methylene]aMino]-;NP-AHD2-;1-[[(2-Nitrophenyl)methylene]amino]-2,4-imidazolidinedione;1-[(2-Nitrobenzylidene)-amino]- imidazolidin-2,4-dione-13C,15N3
• CAS NO: 623145-57-3
• Molecular Formula: C₁₀H₈N₄O₄
• Molecular Weight: 248.19
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 623145-57-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.58±0.1 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly)
• PKA: 7.76±0.10(Predicted)
• CAS DataBase Reference: 2-NP-AHD(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NP-AHD(623145-57-3)
• EPA Substance Registry System: 2-NP-AHD(623145-57-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 623145-57-3(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 623145-57-3 differently. You can refer to the following data:
1. A derivative of the metabolite of nitrofuran antibiotics, 1-aminohydantoin (AH
2. A derivative of the metabolite of nitrofuran antibiotics, 1-aminohydantoin (AH) (A611090).Environmental contaminants; Food contaminants; Heat processing contaminants

Upstream product

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• 6301-02-6 1-aminohydantoin 

Relevant articles and documents

Development of monoclonal antibody-based ultrasensitive enzyme-linked immunosorbent assay and fluorescence-linked immunosorbent assay for 1-aminohydantoin detection in aquatic animals

Monitoring and rapid evaluation of nitrofurantoin metabolite, 1-aminohydantoin (AHD), are important for food safety and human health. Herein, we established the monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) an

Plant Uptake and Metabolism of Nitrofuran Antibiotics in Spring Onion Grown in Nitrofuran-Contaminated Soil

Environmental pollution caused by the discharge of mutagenic and carcinogenic nitrofurans to the aquatic and soil environment is an emerging public health concern because of the potential in producing drug-resistant microbes and being uptaken by food crops. Using liquid chromatography-tandem mass spectrometry analysis and with spring onion (Allium wakegi Araki) as the plant model, we investigated in this study the plant uptake and accumulation of nitrofuran from a contaminated environment. Our study revealed for the first time high uptake and accumulation rates of nitrofuran in the edible parts of the food crop. Furthermore, results indicated highly efficient plant metabolism of the absorbed nitrofuran within the plant, leading to the formation of genotoxic hydrazine-containing metabolites. The results from this study may disclose a previously unidentified human exposure pathway through contaminated food crops.